OAICs AGING Initiative HMORNOAICs AGING Initiative Pilot Projects

– OAICs “AGING” Initiative HMORN-OAICs AGING Initiative Pilot Projects Program Co-Chairs: Pilot Projects Informational Webinar Rebecca A. Silliman MD Ph. D Boston Pepper Center June 1, 2015 Mark C. Hornbrook Ph. D Kaiser Permanente Northwest Center for Health Research

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– OAICs “AGING” Initiative Pilot Projects Solicitation Pilot Project RFA—released May 18, 2015 § Specific Requirements for the Letter of Intent § – Specific Aims (One Page) – Biosketch of PI (new NIH format) § Full specification of the study team is not required for the LOI – Full applications must be a collaborative effort between HMORN and OAIC investigators – Pilot Projects Program can assist in finding a collaborative partner if needed 5 BS

– OAICs “AGING” Initiative LOI Guidelines § Include: § Project title at the top of the page § Paragraph summarizing the significance of the research problem and expected contributions § Format: § 1 -page, single-spaced § 1” margins § 11 - or 12 -point type § Specific aims are likely to be reviewed more favorably if they are well-developed (i. e. , not vague intentions) § Name of the PI is shown by the included biosketch 6 MH

– OAICs “AGING” Initiative Research Priorities--Pilots § Methodological issues relevant to analyses of the health impact or treatment of MCCs including the validity of empirical measures § Methods to address inferential issues in observational data on treatment effects § Novel methods to use information contained in electronic health records to construct new measures relevant to chronic conditions, their treatments, and outcomes § Public health and health care cost impacts of specific combinations of two or more chronic conditions in defined older populations § Effectiveness and safety of different therapeutic options for patients with specific combinations of two or more conditions § Alterations in safety or effectiveness of a treatment for one condition related to the presence of one or more coexisting conditions § Understanding health and access disparities related to MCCs 7 MH

– OAICs “AGING” Initiative LOI Review Criteria In addition to the standard NIH criteria: (1) Study relevance to older adults with MCCs; (2) Leveraging OAIC-related data and/or the unique features of the HMORN and its data; (3) Likelihood that the project team will reflect a new collaboration between OAIC and HMORN investigators; and (4) Likelihood that the proposed study will be completed within one year. 8 MH

– OAICs “AGING” Initiative § # of LOIs Accepted Target number of accepted LOIs ≈ 10 § To maintain a manageable proposal review load § To reduce unnecessary expenditure of effort to develop too many Pilot Project proposals 9 MH

– OAICs “AGING” Initiative Review & Award Schedule § LOI Submission Due Date: 06/23/2015 § Invitations for Full Applications: 07/20/2015 § Full Applications Due: 09/15/2015 § Announcement of Awards: 11/01/2015 10 MH

– OAICs “AGING” Initiative § Discussion Questions? Suggestions? 11 MH

• Kathryn. anzuoni@meyersprimary. org