Number of UK portfolio urology cancer trials Number

Number of UK portfolio urology cancer trials Number of UK urology trials 2014/15 - Q 1&2 2018/19 160 140 120 100 80 60 40 2014/152015/162016/172017/182018/192014/152015/162016/172017/182018/19 Q 1&2 England Scotland Interventional Wales Observational Commercial N Ireland

Number of UK portfolio urology cancer trials per 100, 000 population UK urology cancer trials per 100 k population 2014/15 2017/18 (excluding commercial trials) UK urology cancer trials per 100 k population 2014/15 2017/18 (including commercial & non commercial trials) 0. 8 1 0. 7 0. 9 0. 6 0. 8 0. 5 0. 7 0. 6 0. 4 0. 5 0. 3 0. 4 0. 3 0. 2 0. 1 0 0. 1 2014/15 2015/16 England Scotland 2016/17 Wales 2017/18 N Ireland 0 2014/15 2015/16 England Scotland 2016/17 Wales 2017/18 N Ireland

Recruitment to UK portfolio urology cancer trials Average number of participants in UK cancer trials by trial type England Scotland Wales N Ireland 2014/15 Interventional Observational Commercial 2015/16 67. 1 18. 09524 13. 52941 2016/17 58. 58824 16. 33333 2017/18 51. 1875 2014/15 284. 0476 2015/16 176. 6774 26. 19048 2016/17 257. 5455 2017/18 10. 5 8 8. 4375 8. 75 19. 1 7. 75 8. 333333 24. 5 79. 33333 66. 5 47 21 122. 381 31. 25 4. 5 202. 6333 17. 2 24. 57143 4 2014/15 37. 83333 10. 5 9. 5 0 2015/16 46. 04 10. 5 5. 833333 5 2016/17 53. 6 2017/18 Recruitment per 100 k data & graph received from HCRW 59. 98113 15. 22222 13. 27273 14. 15385 3. 285714 22. 15385 3. 846154 2. 2 3. 5 0

Number of portfolio urology cancer trials in Wales Number of interventional urology cancer trials in Wales by region 2014/15 - Q 1&2 2018/19 25 Number of Interventional trials Betsi Hywel Cadwaladr Dda 2014/15 7 3 2015/16 3 1 2016/17 3 2 2017/18 4 1 20 15 10 5 0 2014/15 2015/16 North 2016/17 South West 2017/18 ABMU Powys Cwm Taf 7 6 3 4 0 0 2 0 0 0 ABMU Powys Cwm Taf 4 2 2 1 0 0 2 2 0 0 Aneurin Bevan 2 1 1 0 Cardiff & Velindre Vale 5 12 3 9 2 12 3 10 Aneurin Bevan 1 0 0 0 Cardiff & Velindre Vale 4 2 1 3 1 1 2 3 2018/19 Q 1&2 South East Number of observational urology cancer trials in Wales by region 2014/15 - Q 1&2 2018/19 16 Number of observational trials Betsi Hywel Cadwaladr Dda 2014/15 3 2 2015/16 4 2 2016/17 3 1 2017/18 4 1 14 12 10 8 6 4 2 0 2014/15 2015/16 North 2016/17 South West 2017/18 South East 2018/19 Q 1&2

Number of portfolio urology cancer trials in Wales Number of commercial urology cancer trials in Wales by region 2014/15 - Q 1&2 2018/19 9 8 7 6 5 4 3 2 1 0 Number of commercial trials Betsi Hywel Cadwaladr Dda 2014/15 0 0 2015/16 0 2 2016/17 0 1 2017/18 0 1 2014/15 2015/16 North 2016/17 South West 2017/18 ABMU Powys Cwm Taf 0 3 2 2 0 0 0 0 Aneurin Bevan 0 0 Cardiff & Velindre Vale 0 2 0 4 0 2 Aneurin Bevan 3 1 1 0 Cardiff & Vale 9 4 3 5 2018/19 Q 1&2 South East Total number of urology cancer trials in Wales by region 2014/15 -Q 1&2 2018/19 45 40 35 30 25 20 15 10 5 0 Total number of trials Betsi Cadwaladr 2014/15 10 2015/16 7 2016/17 6 2017/18 8 2014/15 2015/16 North 2016/17 South West 2017/18 South East 2018/19 Q 1&2 Hywel Dda 5 5 4 3 ABMU Powys Cwm Taf 11 11 7 7 0 0 4 2 0 0 Velindre 16 16 17 15

Recruitment to portfolio urology cancer trials in Wales Recruitment to urology cancer trials in Wales by region 2014/15 Q 1&2 2018/19 450 400 350 300 Betsi Cadwaladr Hywel Dda ABMU Powys Cwm Taf Aneurin Bevan Cardiff & Vale Velindre 250 200 150 100 50 0 2014/152015/162016/172017/182018/192014/152015/162016/172017/182018/19 Q 1&2 Interventional Observational North South West South East Commercial 2014/15 2015/16 2016/17 2017/18 2018/19 Q 1&2 169 33 65 0 21 3 175 119 101 46 59 0 12 8 50 123 49 15 46 0 0 1 10 162 48 16 23 0 0 0 122 98 22 15 22 0 0 0 8 43

Average recruitment to portfolio urology cancer trials in Wales 4 year average recruitment to urology cancer trials per 100 k population (2014/15 -2017/18) 18 16 14 Wales Average recruitment 2015 - 2018 12 10 8 6 4 2 0 North South West South East