Number of UK portfolio haematology trials Number of

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Number of UK portfolio haematology trials Number of haematology trials by UK nation 2014

Number of UK portfolio haematology trials Number of haematology trials by UK nation 2014 -Q 1&2 2019/20 160 140 120 100 80 60 40 20 England Wales Observational Commercial Q 1 N Ireland 0 /2 19 /1 9 20 18 &2 20 /1 8 20 17 /1 7 16 /1 6 20 15 /1 5 20 0 14 20 /2 19 /1 9 &2 Q 1 Scotland Interventional 20 18 /1 8 20 20 17 /1 7 20 16 /1 6 15 /1 5 20 14 0 /2 20 19 20 /1 9 &2 20 18 /1 8 17 /1 7 20 20 16 /1 6 20 15 /1 5 14 /2 0 20 19 /1 9 20 Q 1 &2 20 18 /1 8 20 17 /1 7 16 /1 6 20 15 20 20 14 /1 5 0

Number of UK portfolio haematology trials per 100, 000 population Number of UK haematology

Number of UK portfolio haematology trials per 100, 000 population Number of UK haematology trials per 100 k population 2014 Q 1&2 2019/20 (excluding commercial trials) Number of UK haematology trials per 100 k population 2014 Q 1&2 2019/20 (including commercial and non commercial trials) 1 0. 9 1. 4 0. 8 1. 2 0. 7 1 0. 6 0. 5 0. 8 0. 4 0. 6 0. 3 0. 4 0. 2 0. 1 0 2014/15 2015/16 England 2016/17 Scotland 2017/18 2018/19 Wales N Ireland Q 1&2 2019/20

Recruitment to UK portfolio cancer trials Cancer recruitment per 100 k graph received from

Recruitment to UK portfolio cancer trials Cancer recruitment per 100 k graph received from HCRW Average number of participants per haematology trial England Scotland Wales Interventional 2014/15 52. 7 13. 7 2015/16 44. 6 10. 4 2016/17 41. 3 10. 1 2017/18 36. 4 7. 6 2018/19 28. 8 3. 8 Q 1&2 2019/20 18. 0 0 Observational 2014/15 67. 4 1. 5 2015/16 66. 3 1. 4 2016/17 149. 2 2. 8 2017/18 139. 9 8. 4 2018/19 79. 4 2. 8 Q 1&2 2019/20 130. 4 2. 0 Commercial 2014/15 10. 0 2. 2 2015/16 11. 8 2. 5 2016/17 14. 4 4. 1 2017/18 20. 0 4. 1 2018/19 19. 4 3. 3 Q 1&2 2019/20 6. 3 5. 0 N Ireland 10. 3 13. 8 7. 1 7. 6 5. 8 11. 7 4. 6 6. 6 7. 1 4. 5 4. 0 1. 0 9. 1 2. 0 18. 0 0. 0 40. 7 1. 5 16. 6 7. 0 10. 0 0 12. 5 0 2. 8 2. 0 3. 5 1. 5 4. 0 3. 5 2. 5 10. 0 3. 4 1. 0 2. 1 1. 0

Number of portfolio cancer trials in Wales Interventional haematology studies in Wales by region*

Number of portfolio cancer trials in Wales Interventional haematology studies in Wales by region* 2014 -Q 1&2 2019/20 Number of interventional trials 35 Betsi Cadwaladr 30 25 20 15 10 5 0 2014/15 2015/16 North 2016/17 South West 2017/18 2018/19 Q 1&2 2019/20 2014/15 2015/16 2016/17 2017/18 2018/19 Q 1&2 2019/20 10 Betsi Cadwaladr 2014/15 2015/16 2016/17 2017/18 2018/19 Q 1&2 2019/20 8 6 4 2 2015/16 North 2016/17 South West 3 4 5 7 0 0 1 2 3 0 5 4 0 0 0 2 2 1 1 0 0 Cardiff & Vale 0 0 1 1 Velindre 12 11 16 13 9 7 0 0 1 0 Number of observational trials 12 2014/15 8 7 6 6 3 3 Aneurin Bevan Cwm Taf South East Observational haematology trials in Wales by region* 2014 -Q 1&2 2019/20 0 Hywel Dda Swansea Bay Powys 2017/18 South East 2018/19 Q 1&2 2019/20 Hywel Dda Swansea Bay Powys 1 3 0 1 0 2 3 1 0 0 1 1 0 0 Aneurin Bevan Cwm Taf 0 0 0 1 2 0 1 0 0 Cardiff & Vale. Velindre 0 1 0 0 4 6 3 2 1 0 0 0 1 1 1

Number of portfolio cancer trials in Wales Commercial haematology trials in Wales by region*

Number of portfolio cancer trials in Wales Commercial haematology trials in Wales by region* 2014 - Q 1&2 2019/20 Number of commercial trials 14 Betsi Swansea Hywel Dda Cadwaladr Bay 12 10 8 6 4 2 0 2014/15 2015/16 North 2016/17 South West 2017/18 2018/19 Q 1&2 2019/20 South East Total haematology trials in Wales by region* 2014 -Q 1&2 2019/20 50 45 40 35 30 25 20 15 10 5 0 2014/15 2015/16 2016/17 2017/18 2018/19 Q 1&2 2019/20 2015/16 North 2016/17 South West 2017/18 South East 2018/19 Q 1&2 2019/20 Aneurin Bevan Cwm Taf Cardiff & Vale Velindre 0 0 1 2 4 3 4 0 0 0 3 0 0 0 0 2 2 6 8 8 0 0 0 0 3 0 0 0 7 0 Total number of trials Betsi Cadwaladr 2014/15 Powys 2014/15 2015/16 2016/17 2017/18 2018/19 Q 1&2 2019/20 Swansea Bay Hywel Dda Powys Aneurin Bevan Cwm Taf Cardiff & Vale Velindre 9 10 7 7 4 5 10 9 12 0 2 3 4 0 8 0 0 0 3 4 2 2 0 0 1 0 0 2 14 17 23 24 19 0 0 0 1 2 4 0 7 0 0 1 15 1

Recruitment to haematology trials in Wales by region Recruitment to haematology cancer trials in

Recruitment to haematology trials in Wales by region Recruitment to haematology cancer trials in Wales by region 2014 2019 Total recruitment to haematology trials in Wales 2014/15 2015/16 2016/17 2017/18 450 400 350 300 250 200 150 100 50 Interventional North South West South East Commercial 0 /2 19 /1 9 Q 1 &2 20 18 /1 8 20 17 /1 7 20 16 /1 6 20 15 /1 5 14 20 Observational 20 0 /2 19 /1 9 Q 1 &2 20 18 /1 8 20 17 /1 7 20 16 /1 6 20 15 /1 5 20 0 14 /2 20 19 /1 9 Q 1 &2 20 18 /1 8 20 17 /1 7 20 16 /1 6 20 15 20 20 14 /1 5 0 Betsi Cadwaladr Hywel Dda Swansea Bay Powys Cwm Taf Aneurin Bevan Cardiff & Vale Velindre 2018/19 Q 1&2 2019/20 56 40 83 85 56 57 40 58 18 0 11 0 84 18 0 50 5 0 31 0 0 7 35 0 0 15 0 0 2 1 0 0 5 1 74 0 125 0 107 0 126 10 101 7 42 11

Recruitment to portfolio cancer trials in Wales Average recruitment to haematology trials per 100

Recruitment to portfolio cancer trials in Wales Average recruitment to haematology trials per 100 k population in Wales by region (2014 -2019) 12 10 Wales Average recruitment 2014 - 2019 8 6 4 2 0 North South West South East