Nouaying Kue BME 281 Dermagraft is a dermal

Nouaying Kue BME 281

� Dermagraft® is a dermal substitute that is a result of original human skin. It is a cell based tissue that is grown on a three dimensional scaffold. � A new packet, will contain cells that are important for the wound to heal. � Dermagraft is packaged in 2 in x 3 in rectangles. � Nanoskin is an organic fiber layered skin substitute that acts as a building block for the skin to regrow. � It is also packaged individually, for usage. � The Nanoskin is packaged in boxes of 12 packets which contain 10 cm x 10 cm squares of Nanoskin.

� There are many dermal injuries that are treated by artificial skin. Ø Ø Ø Burns Skin deformations/abrasions Bone regeneration Ulcers Excoriations Epidermolysis Bullosa � There approximately 150, 000 amputations a year. Diabetes is the leading cause of this.

� Artificial skin works by utilizing its coating to protect the affected area from bacteria. � The substitute dermis was designed so that it would not prohibit natural bodily restoration functions. � It provides a layout for the body to follow to reproduce the skin which was once there. � It regulates the humidity and gas conditions inside the wound. � As well, it does not restrict the movement of affected body parts.

� Sixty-four year old female with foot ulcers from a result of Type II diabetes. Took two applications of dermagraft and four months to treat. � Fourty-one year old male, with Type I diabetes ulcer. Took two treatments and five months. � Sixty-seven year old male, with Type II diabetes took a three month weekly treatment.

Sixty-seven year old male Type II Diabetes

� Depending on the brand, using artificial skin can a cheap and cost effective way to recover from ulcers, burns, etc. � The price for a box of Nanoskin is $80. 00 � The application process is fairly easy. � The materials will not prevent you from performing your duties. � They can be easily replaced or removed. � Patients can have a feeling of peace, by removing unsightly injuries that would prevent them from being at their peak mental state. � The treatment is fairly short, 3 -5 month period.

� The price per application of Dermagraft is $1, 500. 00 � Nanoskin, may need to be replaced more often. � The transparent character of the artificial skin will be unsightly for a while.

� Researchers are looking to further develop the uses of artificial skin to target more diseases, such as skin cancer. � Looking to incorporate nano-technology to help speed up the healing process. � Wider array of usage, such as on prosthetics. � For large areas, sensors are to be placed on the substitute skin. � More affordable prices for treatments.

� � � "Bionano Future. " Bionano Future. N. p. , n. d. Web. 12 Oct. 2012. <http: //www. bionanofuture. com/index. html>. Guan, Guoping. "Scaffolds Decorated by In Vivo Environment Improve Cell Proliferation and Wound Healing. " Millennium Web Catalog. N. p. , n. d. Web. 12 Oct. 2012. <http: //0 ieeexplore. ieee. org. helin. uri. edu/xpl/article. Details. jsp? tp=>. "Innovatecs. Co. " Innovatecs. Co. N. p. , n. d. Web. 12 Oct. 2012. <http: //www. innovatecsco. com/>. Kemmerrer, S. V. "Dermagraft Scale-up Case Study. " Millennium Web Catalog. N. p. , n. d. Web. 12 Oct. 2012. <http: //0 ieeexplore. ieee. org. helin. uri. edu/xpl/article. Details. jsp? tp=>. Morgan, J. R. "Growth Factor Delivery from Genetically Modified Skin Grafts. " Millennium Web Catalog. N. p. , n. d. Web. 12 Oct. 2012. <http: //0 ieeexplore. ieee. org. helin. uri. edu/xpl/article. Details. jsp? tp=>. "Wound Care Dressings. " Wound Care Dressings. N. p. , n. d. Web. 12 Oct. 2012. <http: //feetdoc. com/wound_care_dressings. html>.