Normal bacterial flora The normal microbial flora is

Normal bacterial flora

The normal microbial flora is divided into resident and transient flora

NORMAL MICROBIAL FLORA OF SKIN RESIDENT • • Staphylococcus epidermidis Staphylococcus saprophyticus Micrococci Corynebacteria TRANSIENT Sarcina, Bacilli, Candida, Mycobacteria, Enterobacteria

NORMAL MICROBIAL FLORA OF EYE • • Staphylococcus spp. Haemophilus spp. Neisseria spp. Streptococcus spp.

NORMAL MICROBIAL FLORA OF MOUTH • • • Staphylococcus epidermidis Staphylococcus saprophyticus Staphylococcus aureus Streptococcus mitis Streptococcus salivarius Streptococcus pyogenes Streptococcus pneumonia Neisseria spp. Moraxella spp. Veilonella spp. • • • Actinomyces spp. Lactobacillus spp. E. coli Klebsiella spp. Enterobacter spp. Bacteroides spp. Fusobacterium spp. Treponema denticola Treponema refringens Mycoplasms spp. Candida spp.

NORMAL MICROBIAL FLORA OF STOMACH • • Streptococcus spp. Lactobacillus spp. Candida spp. Helicobacter spp.

NORMAL MICROBIAL FLORA OF SMALL INTESTINE • • • Peptostreptococcus spp. Porphyromonas spp. Bifidobacterium spp. Veilonella spp. Streptococcus spp. Lactobacillus spp.

NORMAL MICROBIAL FLORA OF LARGE INTESTINE • • E. coli Bacteroides spp. Porphyromonas spp. Bifidobacterium spp. Eubacterium spp. Veilonella spp. Peptococcus spp. Enterococcus spp. • • Clostridium spp. Proteus spp. Pseudomonas spp. Mycoplasma spp. Candida spp. Streptococcus spp. Lactobacillus spp.

NORMAL MICROBIAL FLORA OF RESPIRATORY TRACT • • Staphylococcus epidermidis Staphylococcus saprophyticus Staphylococcus aureus Streptococcus pyogenes Neisseria spp. Moraxella lacunata Corynebacterium spp.

NORMAL MICROBIAL FLORA OF THROAT, TONSILS • • • Staphylococcus epidermidis Staphylococcus saprophyticus Streptococcus pyogenes Neisseria spp. Haemophilus spp. Veilonella spp. • Actinomyces spp. • Bacteroides spp. • Fusobacterium spp.

NORMAL MICROBIAL FLORA OF ANTERIOR URETHRA • • • Lactobacillus spp. Streptococcus spp. Staphylococcus spp. Peptostreptococcus spp. Corynebacterium spp. Mycobacterium smegmatis

NORMAL MICROBIAL FLORA OF VAGINA • • Lactobacillus spp. Staphylococcus spp. Mycoplasma spp. Enterobacteria • • Peptostreptococcus spp. Bifidobacterium spp. Bacteroides spp. Fusobacterium spp.

Positive role of normal flora 1. 2. 3. 4. Production of enzymes Protective Synthetic Immunogenic

Negative role of normal flora 1. Some of representatives of normal microbial flora may cause infectious diseases. 2. Produce harmful for human`s organisms products of their metabolism. 3. May be source of endogenous infection. 4. Representatives of normal flora are able to pinch pathogenic variants.

DYSBIOS – is qualitative and quantitative alliterations of normal microbial flora, induced by violation of ecological balance between microbial population of microbial flora.

Dysbios can be induced by • • Prolonged therapy with antibiotics, hormones. Radiation sickness. Radiation and immunosuppressive treatment. Infections of gastrointestinal tract, another infections, cancer, immunodeficiency. • Alterations of diet and deficiency of vitamins in food. • Prolonged stay in hospital (infection by nosocomial strains) and in exclusive space (in space, in submarines).

Principles of dysbios treatment • • • Bacteriotherapy with eubiotics (probiotics). Selective decontamination. Nonspecific immunostimulation. Immunotherapy. Common gnotobiological isolation.