NEWCASTLE PROBLEMNDE YAPILMASI VE YAPILMAMASI GEREKENLER Uzm Vet

NEWCASTLE PROBLEMİNDE YAPILMASI VE YAPILMAMASI GEREKENLER Uzm. Vet. Hekim Güney GÖKÇELİK

NEWCASTLE • PARAMYXOVİRUS • GENOTİP / 1 --->9

VİRÜLANS VE TROPİZM • • • VİSSEROTROPİK VELOJENİK (EKSOTİK NEWCATL) NÖROTROPİK VELOJENİK PNÖMOTROPİK MEZOJENİK RESPİRATORİK LENTOJENİK ENTEROTROPİK APATOJENİK

INCUBATION PERIOD IS VARIABLE • According to virulence, population and susceptible shows the variability of 2 -15 days. • Expected , between 2 -6 days in chickens.

MORBİDİTE/MORTALİTE YÜKSEKTİR • Lentojenik suşlarda morbidite yüksekken mortalite önem kazanmaz • Mezojenik suşlarda yine yüksek morbidite ve % 10’lara varabilecek mortalite beklenebilir • Velojenik suşlarda, aşısız hayvanlarda morbidite ve mortalite % 100’e ulaşır • Aşılanmış hayvanlarda bile % 30 ile 90 arasında değişen mortalite bildirilmiştir

Örnek aşı virus sujlarının virulans(ve ICPI) ve tropizm özelliklerine göre sınıflandırılması (VAN ECK ve ark. , 1991 ; ALEXANDER, 1998) VİRULANS AŞI VİRUSU ICPI TOPİZM Mezojenik (ICPI =1 ila 2) Roakin Komarov 1, 45 1, 41 Respiratorik Lentojenik Lasota 0, 44 Respiratorik (ICPI=0, 2 İLA 0, 7) F VG / GA Hitchner B 1 0, 25 0, 2 Respiratorik Enterik Respiratorik Ulster 2 C Phy LMV 42 0, 04 ila 0, 2 0, 16 Enterik Apatojenik (ICPI = 0, 0 ila 0, 2)

SENSITIVE SPECIES – – – – – 236 bird species have been reported to be sensitive The most sensitive are chicken. Goose- ducks not show clinical sign, might be carrier Turkeys are more serious spreader than chickens Waterfowl are emit and carry lentogenic strains. Also pigeons are endemic to lentogenic and mesogenic strains. Nervous signs characterized in cormorant. Many different forms consist in Pisittasins. Nervous signs are observed in ripper birds. Respiratory problems are discovered in ostriches.

RESİSTANT VİRUS • Suspect flock; -11 C – 36 C up to 255 days, • In 8 C 14 months and in freezing weather condition for years , • 300 days of carcasses of bone marrow , • Intensive carcass consuming dogs 22 days, • In Turkey intestines until 12 months, • In summer term 7 days, in spring 14 days and in winter 30 days have been reported to survive.

RESISTANT VİRUS • In contaminated materials 10 -14 days, • In soil 20 C , 22 days , • Earth worms 4 -18 days, • In experimental contaminated lake water have been reported to survive 11 -19 days.

PROPAGATION IS VERY EFFECTIVE • 3 -4 days after infection by feces and 3 -4 weeks by droplet and feces • Feed, Water, Tools, Pad, Equipment, People, Frozen meat, disposable nature of the dead, wild birds, • Maggots, Mites, Rabbit, Cat- Dogs, contamination from infected breders egg shell

FASTER DISPERSION • Agent, can reach in a calm air condition 50 m and the wind event 1 -2 km far away.

MISTAKES RELATED WITH PRODUCERS • Do not want to warning • Besides poultry houses, kept broiler or laying hens • Feed cats and dogs • Even with next-door neighbour not to share their problems • In case of problem, do not take a joint decision

MISTAKES RELATED WITH VETERINARIAN PROFILE • • • Poultry species, age, susceptibility Factor strain, virulence Vaccination schedule Enviromental condition Secunder infections VARIABILITY FIGHT SCHEDULE

DO WE REFER TRUE? • • Clinical and necroscopic error Smiliar disease Business blindness Durable insistence

OTHERS • To ignore, application of Gumboro hot vaccine or other immünosüpressif agents • Vaccination according to company-producers pressure or wrong suggestions way • Failure to report under pressure of Company. Producers • Do not warn, around producers

NEGATİVE EFFECTS RELATED WİTH STATE • In fight main and general measures should be recommended by the Ministry and maintained under control. • Epidemiological surveillance by computer and recording system should be establish. • In fight diseases should be the right sort of • Between science and practical disconnection should be corrected and work together.

GOVERNMENTAL… • Ministry officials, field staff and producers provided co-operation to each other. • All staffs beyond the fuzz behaviour must have sufficient knowledge and having discretionary • Country poultry vaccination must be controlled

DURING THE EPIDEMIC NECESSITIES • Do not make faster dispersion that consider evaulation of sick chickens and make them cut • Do not carry sick chickens where there is no disease • Every two hours collect all the dead and burn them • Cleaning the rest of the coops, do not put chıicks at least 1 month. • When you realize, it will be too late thus do not have any hopes from vaccination sick animals. • Warn surroundings • Accept, the importance of vaccination and biosecurity is equal 50% of the rate.

KÜMES TEMİZLİĞİNDE • Virus; 100 C’de 1 dk ve 56 C’de 3 saatte inaktive olur • Güneşin direkt UV ışınları 15 dk içerisinde öldürücüdür • Eter, Fenoller, Formalin ve İyot’lu dezenfektanlar etkindir.

DİNLEDİĞİNİZ VEDE UYGULAYACAĞINIZ İÇİN TEŞEKKÜR EDERİM