NEOPLASIA Dr Osama I Nassif MD FRCPC Associate

NEOPLASIA Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. ������

Dr. Osama I Nassif. MD, FRCPC. NEOPLASIA Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. Associate professor & consultant pathologist. Pathology Dept. King Abdullaziz University. NEOPLASIA

Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. NEOPLASIA What Why Where When How

NEOPLASIA Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. Definition : An abnormal mass the growth of which exceeds and is uncoordinated with that of the normal tissue and persists in the same excessive manner after the cessation of stimuli which evoked the change.

NEOPLASIA Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. DIFINITIONS Ø TUMOR VS NEOPLASM Ø ONCOLOGY= ONCOS + LOGOS Ø BENIGN = RELATIVELY INNOCENT Ø MALIGNANT = CANCER ( CRAB )

NEOPLASIA Nomenclature Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University.

NEOPLASIA Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. Benign tumors: oma + cell type Papilloma : benign surface neoplasm

NEOPLASIA Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. Benign tumors n A Polyp : mass projecting above a mucosal surface

NEOPLASIA Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. Benign tumors n An Adenoma: benign epithelial neoplasm producing or arising from glands

NEOPLASIA Benign tumors Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. connective tissue Leiomyoma : A benign neoplasm of smooth muscle

NEOPLASIA n Leiomyoma Dr. Osama I Nassif. MD, FRCPC. DR OSAMA I NASSIF FRCPC Associate professor & consultant pathologist. NEOPLASIA LEIOMYOMA HPF Pathology Dept. King Abdulaziz University.

NEOPLASIA Nomenclature Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University.

NEOPLASIA Benign tumors n Fibroadenoma : more than one cell type , from one germ layer Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University.

NEOPLASIA Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. Benign tumors n Mixed tumor of salivary glands (pleomorphic adenoma) Derived from one germ layer

NEOPLASIA Nomenclature Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University.

NEOPLASIA Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. Benign neoplasms n Mature teratoma : more than one neoplastic cell type derived from more than one germ layer.

NEOPLASIA Malignant tumors Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University.

NEOPLASIA Benign Vs malignant Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University.

Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. NEOPLASIA Malignant neoplasms differentiation and anaplasia n Adenocarcinoma

NEOPLASIA Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. Malignant neoplasms Squamous cell carcinoma: Well-differentiated. Differentiation and anaplasia

Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. NEOPLASIA Benign vs Malignant

NEOPLASIA Anaplasia n Pleomorphism n Hyperchromasia n High N/C ratio n Polynuclearity n High mitotic rate n Bizarre shapes/sizes n Atypical mitoses Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University.

Dr. Osama I Nassif. MD, FRCPC. Associate professor & consultant pathologist. Pathology Dept. King Abdulaziz University. NEOPLASIA HAVE A NICE DAY