Ne SSI Gen III Finding the Longitude the

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Ne. SSI™ - Gen III Finding the Longitude – the micro. Analytical Vision Rob

Ne. SSI™ - Gen III Finding the Longitude – the micro. Analytical Vision Rob Dubois CPAC/Ne. SSI™ Workshop – PM Session Seattle, Washington, USA May 6, 2004 “the best way to predict the future is to create it” rnd/May 6, 2004

Who is John Harrison? Courtesy of ©NMM London. 1693 -1776 Like squaring the circle

Who is John Harrison? Courtesy of ©NMM London. 1693 -1776 Like squaring the circle or inventing a perpetual motion machine, the phrase 'finding the longitude' became a sort of catchphrase for the pursuits of fools and lunatics. Many people believed that the problem simply could not be solved. rnd/May 6, 2004 2

Today’s Analytical System The Technology of Last Resort! • More of an “art” than

Today’s Analytical System The Technology of Last Resort! • More of an “art” than a “science” • Expensive – up to 60% of costs after purchase • Require large sample & utility usage • Skilled maintenance staff required Courtesy of Dow Chemical, Freeport, TX rnd/May 6, 2004 3

Micro. Analytical & Process Analytical Smaller Size Higher System Reliability Technology Explosion! • Fast

Micro. Analytical & Process Analytical Smaller Size Higher System Reliability Technology Explosion! • Fast networks/computers • Robust/miniature electronics • Lab-on-a-chip; optics; wireless By-Line/In-Line • Fiber optic sensors What does the Market Need? • Reliable, rugged, low cost & fast What are the Critical Issues? • Development Cost Engineered Analyzer House • Technology hurdles Ad Hoc Installations 1938 rnd/May 6, 2004 • Market acceptance Time 2000 4

The Ideal micro. Analytical Device for Process Analytical (1/4) • • Has global electrical

The Ideal micro. Analytical Device for Process Analytical (1/4) • • Has global electrical (hazardous) Certifications Embedded multi-drop digital protocol Plug & Play (self-identifies) Robust (> 99. 9% uptime) – Embedded smarts/Self-diagnostics – minimum or no moving parts – modular replacement • Low cost (c. <$5 K) – <$1 K “disposable” • Embedded documentation rnd/May 6, 2004 5

The Ideal micro. Analytical Device for Process Analytical (2/4) • Multi-Component Analysis – multi-component:

The Ideal micro. Analytical Device for Process Analytical (2/4) • Multi-Component Analysis – multi-component: GC, MS, SPECTROSCOPY – unimolecular sensors • Suitable for operating as a Functional Clusters – p. H, DO 2, Conductivity: “water package” – NOx, O 2, CO: “CEMS package” • Gas and/or Liquid Service • Wide Sensitivity: “Configurable” rangeability – PPB, PPM, PERCENT rnd/May 6, 2004 6

The Ideal micro. Analytical Device (3/4) • • Fast (continuous) Response (< 10 seconds)

The Ideal micro. Analytical Device (3/4) • • Fast (continuous) Response (< 10 seconds) Physically small in size Low Power (for intrinsic safe operation) Impeccable selectivity – under both normal & upset conditions 316 L SS (typ. ) or process compatible Self Correcting (drift compensation within limits) – Ambient temp/pressure changes – Sample pressure/flow/temp changes Self-checking/calibrating Low/No Utility or Reagent Usage rnd/May 6, 2004 7

The Ideal micro. Analytical Device (4/4) (conditioned sample) • Typ. Pressure: – (typical) vacuum

The Ideal micro. Analytical Device (4/4) (conditioned sample) • Typ. Pressure: – (typical) vacuum to 150 psig – (higher) vacuum to 500 psig • Typ. Temperature: -20 to 80 C. • Flow (gas) – 3 to 200 cc/min and 3 to 2, 000 cc/min • Flow (liquid) – 1 to 300 cc/min and 1 to 1, 500 cc/min rnd/May 6, 2004 8

Analytical Sensors (Gen III) Fiber Optic SAM AT One Sensor measuring Multiple Analytes V

Analytical Sensors (Gen III) Fiber Optic SAM AT One Sensor measuring Multiple Analytes V One sensor per component “lab on a chip” T P A rnd/May 6, 2004 9

Ne. SSI™: Enabler for Micro. Analytical Standard (the “rail” concept) “connectivity ” Standard Electrical

Ne. SSI™: Enabler for Micro. Analytical Standard (the “rail” concept) “connectivity ” Standard Electrical (Digital) Interface “Rail” Anyone’s Sensor P Anyone’s Actuator V SAM* Standard “hockey-puck. PC” Standard Mechanical Interface “Rail” rnd/May 6, 2004 *Sensor/Actuator Manager 10

Ne. SSI™ an Enabling Technology for micro. Analytical • provides clear “standards” • lowers

Ne. SSI™ an Enabling Technology for micro. Analytical • provides clear “standards” • lowers infrastructure development costs and associated entry risk (faster to market) • developer can concentrate on providing a premiere micro. Analytical sensor – rather than infrastructure rnd/May 6, 2004 11

Water “Cluster” Measurement rnd/May 6, 2004 Sensor Capsule Courtesy of Predictive Controls 12

Water “Cluster” Measurement rnd/May 6, 2004 Sensor Capsule Courtesy of Predictive Controls 12

micro. GC Network D/A A/D Mod Valve Press/ Temp Substrate On/Off and Modulating valves

micro. GC Network D/A A/D Mod Valve Press/ Temp Substrate On/Off and Modulating valves rnd/May 6, 2004 Other Analytical: Ion, Nox. O 2, p. H Conductivity, NOx, Turbidity, Density, Opacity Refractive Index, Others Chemometric Sensors for Complex Analytical Measurements. Substrate Flow Sensor w/ Temp, Pressure w/ Temp PHASED * Micro GC Moisture in Dry Gases *PHASED: Courtesy of Honeywell 13

Conclusion • Ne. SSI™ provides an enabling platform for micro. Analytical • micro. Analytical

Conclusion • Ne. SSI™ provides an enabling platform for micro. Analytical • micro. Analytical will provide the greatest value and impact to End Users • Just like John Harrison, finding the longitude in micro. Analytical, is fast becoming a reality. rnd/May 6, 2004 Courtesy of ©NMM London Solution to longitude problem – a miniature, accurate, 14 seaworthy timepiece.