Musculoskeletal System Components Skeletal Muscles Bones Joints 12222021
Musculoskeletal System Components § Skeletal Muscles § Bones § Joints 12/22/2021 1
Musculoskeletal System Components Skeletal Muscles • Attachment: –Where & How • Fibre Direction: – In Relation to the Axis of Moving Part – In Relation to Joint Concerned • Types of Skeletal Muscle Fibres 12/22/2021 2
Over View of Musculoskeletal System What are the main tissues that form this system? 1. Skeletal Muscles 2. Connective Tissue Proper 3. Specialized Connective Tissue A. Bones B. Cartilages C. Tendons. . etc 12/22/2021 3
The Musculoskeletal System What Should I Know About Skeletal Muscles? 1) Striated Muscle: A. Striations, B. Nuclear Position C. Periphery of fibres’ Cross Section. 12/22/2021 4
The Musculoskeletal System 2. What is a Motor Unit? Definition/fibre numbers/neuronal connection What is its Histochemical or Functional type? 3. Attachments: Where in relation to the axis of movement? Relation & How far from the joint concerned? 12/22/2021 5
What Should I Know About Skeletal Muscles? 1) Joint’s Relation: Is it In front, Behind, Medial or Lateral? 1) What are (is) - Spinal Level of their (its) innervation? Neuronal nuclei as functional groups? 2) What are their actions on concerned joints? 6 12/22/2021 6
An Over View of the Musculoskeletal System A. Flexors, 1 B. Extensors, 2 C. Abductors, 3 D. Adductors, 4 E. Rotators, 5 F. Stabilizers or Fixaters, 6 G. Anti Spin, 7 12/22/2021 7
An Over View of the Musculoskeletal System A. B. C. D. Connective tissue proper Adipose Tissue Dense Connective Tissue Reticular Connective Tissue 12/22/2021 8 8
An Over View of the Musculoskeletal System Specialized Connective Tissue: 1. Bone 2. Cartilage ( extra cellular matrix is mainly collagen). Embryonic Connective Tissues: 1. Mesenchymal Connective Tissue 2. Mucous Connective Tissue 12/22/2021 9 9
Fibre Types § Collagenous fibers § § Elastic fibers § § Reticular fibers 12/22/2021 10
Fibre Types & Disorders of Connective Tissue • Collagenous fibers • Elastic fibers • Reticular fibers Disorders of connective tissue: • Inherited, • Environmental. Inherited Marfan syndrome – A genetic disease causing Abnormal Fibrillin 12/22/2021 11 11
q q Ehlers-Danlos Syndrome - Deficient Type III Collagen a genetic disease causing progressive deterioration of collagens, with different EDS types affecting different sites in the body, such as joints, heart valves, organ walls, arterial walls, etc. Loeys-Dietz syndrome - A genetic disease related to Marfan syndrome, with an emphasis on vascular deterioration. Pseudoxanthoma elasticum - an autosomal recessive hereditary disease, caused by calcification and fragmentation of elastic fibres, affecting the skin, skin the eyes and the cardiovascular system Osteogenesis imperfecta (Brittle Bone Disease) Disease caused by insufficient production of good quality collagen to produce healthy, strong bones. 12 12/22/2021 12
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q Fibrodysplasia Ossificans Progressiva - disease of the connective tissue, caused by a defective gene which turns connective tissue into bone. q Spontaneous Pneumothorax - Believed to be related to subtle abnormalities in connective tissue. q Sarcoma - A neoplastic process originating within connective tissue. Environmental q Scurvy - caused by a dietary deficiency in vitamin C, C leading to abnormal collagen q Systemic lupus erythematosus? - a chronic, multisystem, inflammatory disorder of probable autoimmune etiology, occurring predominantly in young women 12/22/2021 14 14
q Fibrodysplasia Ossificans Progressiva - disease of the connective tissue, caused by a defective gene which turns connective tissue into bone. q Spontaneous Pneumothorax - Believed to be related to subtle abnormalities in connective tissue. q Sarcoma - A neoplastic process originating within connective tissue. Environmental q Scurvy - caused by a dietary deficiency in vitamin C, C leading to abnormal collagen q Systemic lupus erythematosus? - a chronic, multisystem, inflammatory disorder of probable autoimmune etiology, occurring predominantly in young women 12/22/2021 15 15
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Types of Collagen 12/22/2021 17
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