Molecularscale surface analytics Giovanni Costantini Department of Chemistry

Molecular-scale surface analytics Giovanni Costantini Department of Chemistry, University of Warwick, UK

Our instruments • 4 STM instruments LT-UHV Createc VT-UHV Specs RT-UHV Omicron ambient • 2 ESI-deposition setups O’Spray SEISMIC • XPS-UPS Warwick Interdepartmental Photoemission Facility • Synchrotron (NIXSW in particular, IO 9 @ Diamond) 2

Polymer Analytics A B 2 nm B A A BB 1 nm A B A D. A. Warr, et al. , Sci. Adv. 4, eaas 9543 (2018) 3

Ultrahigh Resolution Molecular Imaging for Chemical Structure Determination © IBM Zürich The central idea of this project is to exploit the unparalleled spatial resolution of UHVSPM to solve a fundamental analytical problem: determining the exact chemical structure of an unknown molecule. Our proposed solution is extremely simple but, at the same time, potentially transformative: adsorb the molecule onto a surface and just take a picture of it. A. Mistry, et al. , hem. : Eur. J 21, 2011 (2015) 4

“It would be very easy to make an analysis of any complicated chemical substance; all one would have to do would be to look at it and see where the atoms are”. (There's Plenty of Room at the Bottom, 1959) 5

Automating scanning probe microscopy Necessary condition to make SPM into a “real” and useful analytical technique. (towards a “push button” technique) Main objectives: • Tip preparation • Image recognition (chemical structure determination) 6

Machine Learning collaborations Andrea Cavallaro Professor of Multimedia Signal Processing, QMUL Director of the Centre for Intelligent Sensing. QMUL 20+ years of research (well before the hype!) in ML applied to automated vision, image recognition, audio detection Current research interests: Robotic perception, Camera networks, Multimodal information fusion, Underwater imaging, Privacy-by-design. 7