Molecular Mechanism of Regulation of the Atypical Protein

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Molecular Mechanism of Regulation of the Atypical Protein Kinase C by N-terminal Domains and

Molecular Mechanism of Regulation of the Atypical Protein Kinase C by N-terminal Domains and an Allosteric Small Compound Hua Zhang, Sonja Neimanis, Laura A. Lopez-Garcia, José M. Arencibia, Sabine Amon, Adriana Stroba, Stefan Zeuzem, Ewgen Proschak, Holger Stark, Angelika F. Bauer, Katrien Busschots, Thomas J. D. Jørgensen, Matthias Engel, Jörg O. Schulze, Ricardo M. Biondi Chemistry & Biology Volume 21 Issue 6 Pages 754 -765 (June 2014) DOI: 10. 1016/j. chembiol. 2014. 007 Copyright © 2014 Elsevier Ltd Terms and Conditions

Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007) Copyright ©

Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007) Copyright © 2014 Elsevier Ltd Terms and Conditions

Figure 1 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007)

Figure 1 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007) Copyright © 2014 Elsevier Ltd Terms and Conditions

Figure 2 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007)

Figure 2 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007) Copyright © 2014 Elsevier Ltd Terms and Conditions

Figure 3 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007)

Figure 3 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007) Copyright © 2014 Elsevier Ltd Terms and Conditions

Figure 4 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007)

Figure 4 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007) Copyright © 2014 Elsevier Ltd Terms and Conditions

Figure 5 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007)

Figure 5 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007) Copyright © 2014 Elsevier Ltd Terms and Conditions

Figure 6 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007)

Figure 6 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007) Copyright © 2014 Elsevier Ltd Terms and Conditions

Figure 7 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007)

Figure 7 Chemistry & Biology 2014 21754 -765 DOI: (10. 1016/j. chembiol. 2014. 007) Copyright © 2014 Elsevier Ltd Terms and Conditions