Mitochondrial Respiratory Dysfunction Induces Claudin1 Expression via Reactive

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Mitochondrial Respiratory Dysfunction Induces Claudin-1 Expression via Reactive Oxygen Species-mediated Heat Shock Factor 1

Mitochondrial Respiratory Dysfunction Induces Claudin-1 Expression via Reactive Oxygen Species-mediated Heat Shock Factor 1 Activation, Leading to Hepatoma Cell Invasiveness* Jong-Hyuk Lee, Young-Kyoung Lee, Jin J. Lim, Hae-Ok Byun, Imkyong Park, Gyeong-Hyeon Kim, Wei Guang Xu, Hee-Jung Wang, Gyesoon Yoon Journal of Biological Chemistry Volume 290 Issue 35 Pages 21421 -21431 (August 2015) DOI: 10. 1074/jbc. M 115. 654913 Copyright © 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions

FIGURE 1 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115.

FIGURE 1 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115. 654913) Copyright © 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions

FIGURE 2 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115.

FIGURE 2 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115. 654913) Copyright © 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions

FIGURE 3 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115.

FIGURE 3 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115. 654913) Copyright © 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions

FIGURE 4 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115.

FIGURE 4 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115. 654913) Copyright © 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions

FIGURE 5 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115.

FIGURE 5 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115. 654913) Copyright © 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions

FIGURE 6 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115.

FIGURE 6 Journal of Biological Chemistry 2015 29021421 -21431 DOI: (10. 1074/jbc. M 115. 654913) Copyright © 2015 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions