MICA polymorphism identified by whole genome array associated

MICA polymorphism identified by whole genome array associated with NKG 2 D-mediated cytotoxicity in T-cell large granular lymphocyte leukemia by Aaron D. Viny, Michael J. Clemente, Monika Jasek, Medhat Askar, Hemant Ishwaran, Amy Nowacki, Aiwen Zhang, and Jaroslaw P. Maciejewski haematol Volume 95(10): 1713 -1721 September 30, 2010 © 2010 by Ferrata Storti Foundation

Characteristics of the cohort of patients with LGL leukemia. Aaron D. Viny et al. Haematologica 2010; 95: 1713 -1721 © 2010 by Ferrata Storti Foundation

Illumina platform ‘random forest’ results for patients with LGL leukemia versus healthy and disease controls. Aaron D. Viny et al. Haematologica 2010; 95: 1713 -1721 © 2010 by Ferrata Storti Foundation

Illumina platform ‘exemplar’ results for patients with LGL leukemia versus healthy and disease controls. Aaron D. Viny et al. Haematologica 2010; 95: 1713 -1721 © 2010 by Ferrata Storti Foundation

Workflow diagram for identification of SNP rs 1063635 and association with MICA 00801/A 5. 1. Aaron D. Viny et al. Haematologica 2010; 95: 1713 -1721 © 2010 by Ferrata Storti Foundation

(A) Flow cytometry results. Aaron D. Viny et al. Haematologica 2010; 95: 1713 -1721 © 2010 by Ferrata Storti Foundation

Cytotoxicity assay results. Aaron D. Viny et al. Haematologica 2010; 95: 1713 -1721 © 2010 by Ferrata Storti Foundation

MICA SNP genotypes. Aaron D. Viny et al. Haematologica 2010; 95: 1713 -1721 © 2010 by Ferrata Storti Foundation