Metalfree Superoxide Dismutase1 and Three Different Amyotrophic Lateral

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Metal-free Superoxide Dismutase-1 and Three Different Amyotrophic Lateral Sclerosis Variants Share a Similar Partially

Metal-free Superoxide Dismutase-1 and Three Different Amyotrophic Lateral Sclerosis Variants Share a Similar Partially Unfolded β-Barrel at Physiological Temperature* Armando Durazo, Bryan F. Shaw, Madhuri Chattopadhyay, Kym F. Faull, Aram M. Nersissian, Joan Selverstone Valentine, Julian P. Whitelegge Journal of Biological Chemistry Volume 284 Issue 49 Pages 34382 -34389 (December 2009) DOI: 10. 1074/jbc. M 109. 052076 Copyright © 2009 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions

FIGURE 1 Journal of Biological Chemistry 2009 28434382 -34389 DOI: (10. 1074/jbc. M 109.

FIGURE 1 Journal of Biological Chemistry 2009 28434382 -34389 DOI: (10. 1074/jbc. M 109. 052076) Copyright © 2009 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions

FIGURE 2 Journal of Biological Chemistry 2009 28434382 -34389 DOI: (10. 1074/jbc. M 109.

FIGURE 2 Journal of Biological Chemistry 2009 28434382 -34389 DOI: (10. 1074/jbc. M 109. 052076) Copyright © 2009 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions

FIGURE 3 Journal of Biological Chemistry 2009 28434382 -34389 DOI: (10. 1074/jbc. M 109.

FIGURE 3 Journal of Biological Chemistry 2009 28434382 -34389 DOI: (10. 1074/jbc. M 109. 052076) Copyright © 2009 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions

FIGURE 4 Journal of Biological Chemistry 2009 28434382 -34389 DOI: (10. 1074/jbc. M 109.

FIGURE 4 Journal of Biological Chemistry 2009 28434382 -34389 DOI: (10. 1074/jbc. M 109. 052076) Copyright © 2009 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions

FIGURE 5 Journal of Biological Chemistry 2009 28434382 -34389 DOI: (10. 1074/jbc. M 109.

FIGURE 5 Journal of Biological Chemistry 2009 28434382 -34389 DOI: (10. 1074/jbc. M 109. 052076) Copyright © 2009 ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. Terms and Conditions