METABOLISME BAKTERI Metabolism Bioenergetics Catalysis Enzymes Oxidation Reduction

METABOLISME BAKTERI

Metabolism Bioenergetics Catalysis & Enzymes Oxidation Reduction Electron Donors & Acceptors Energy Storage Catabolisme Anabolism Glycolysis Biosynthesis of Sugar Respiration Biosynthesis of Amino Acids & Nucleotides Proton Motive Force Citric Acid Cycle Catabolyc diversity Biosynthesis of Fatty Acids & Lipids Regulating the activity of biosynthetic enzymes

LEARNING OBJECTIVES Define metabolism, and describe the fundamental difference between anabolism & catabolism Identify the role of ATP as an intermediate between catabolism & anabolism

Metabolisme : semua reaksi kimia yang terjadi di dalam sel untuk kelangsungan hidup sel tersebut Anabolisme : sintesis molekul komplek dari molekul sederhana yang membutuhkan energi untuk reaksinya Katabolisme : perombakan molekul komplek menjadi molekul sederhana yang menghasilkan energi dari reaksinya

Catabolic reaction provide building blocks for anabolic reactions This coupling of energy-requiring and energy releasing reactions is made possible through the molecule ATP stores energy derived from catabolic reactions and release it later ti drive anabolic reactions When the terminal phosphate group is split from ATP, ADP is formed, and energy is release to drive anabolic reaction ATP ADP + Pi + energy Energy from catabolic reactions is used to combine ADP and P to resynthesize ATP ADP + Pi + energy ATP

ANABOLISM Energy requiring reaaction Building of complex organic molecules from simpler ones These reaction are called anabolic or biosynthetic Dehydration synthesis reactions that release water Endergonic consume more energy than they produce Ex: Formation of proteins from amino acids, nucleic acids from nucleotides, and polysaccharides from simple sugar

NITROGEN SYNTHESIS

CARBOHYDRATE SYNTHESIS

CATABOLIS M Release Energy Breakdown of complex organic compound into simpler ones These reaction are called catabolic or degradative Hydrolytic reactions which use water and in which chemical bonds are broken Exergonic produce more energy than they consume Ex: when cells break down sugars into carbondioxide and water

Jenis fermentasi Produk yang Contoh bakteri dihasilkan Homolactat Asam laktat Streptococcus, Lactobacillus, Bacillus Alchololic Propionic Etil alkohol & CO 2 Saccharomyces As. propionat, as. Asetat&CO 2 Propionibacterium Mixed acid As. Asetat, as. suksinat, etil alkohol, CO 2& H 2 O Escherichia coli, dan beberapa Enterobacteriaceae Butanediol Butylene glikol & CO 2 Non. Enterobacteriaceae Butyric As. butirat, isopropil alk. , etil alk, CO 2 Clostridium