MedicineInduced Psychosis An Officers Story Officer Bradley Colas

Medicine-Induced Psychosis: An Officer’s Story Officer Bradley Colas Virginia Beach Police Department

Clarithromycin (BIAXIN)

Twenty-Five Years of Pharmaceutical Industry Criminal and Civil Penalties: 1991 Through 2015 - Sammy Almashat, M. D. - M. P. H. Sidney M. Wolfe, M. D. - Michael Carome, M. D. • “From 1991 through 2015, a total of 373 settlements were reached between the federal and state governments and pharmaceutical manufacturers, for a total of $35. 7 billion. ” 1 • “Financial penalties continued to pale in comparison to company profits, with the $35. 7 billion in penalties from 1991 through 2015 amounting to only 5% of the $711 billion in net profits made by the 11 largest global drug companies during just 10 of those 25 years (2003 -2012). ” 1 1 - Almashat, S. , Wolfe, S. , & Carome, M. (2016). Twenty-Five Years of Pharmaceutical Industry Criminal and Civil Penalties: 1991 Through 2015. Public Citizen. Retrieved from https: //www. citizen. org/sites/default/files/2311. pdf

Clarithromycin (BIAXIN) • Portuguese Medical Journal: “Antibiomania, or mania induced by antibiotics, is a rare, but important side effect of clarithromycin and other antibiotics…” 2 • Journal of Clinical Psychopharmacology: According to a professional review of antibiotic-induced manic episodes, “cases reported by the FDA showed clarithromycin and ciprofloxacin to be the most frequently associated with the development of mania. ” 3 • Meyler’s Side Effects of Drugs (15 th ed. ): “Adverse events on the nervous system due to clarithromycin have been observed in 3% of patients. ” 4 2 - Lopes R, Rodrigues R, Domingues I, Curral R, Roma-Torres A: [Antibiomania: a case of a manic episode induced by clarithromycin]. Acta Med Port 2011, 24(5): 827– 832. 3 - Abouesh A, Stone C, Hobbs WR. Antimicrobial-induced mania (antibiomania): a review of spontaneous reports. J Clin Psychopharmacol 2002; 22(1): 71– 81. 4 - Aronson JK, ed. Meyler’s Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Vol 1. 15 th ed. Amsterdam, Netherlands: Elsevier; 2006: xi-xiii.

Objectives • 1. ) Participants will be able to describe three practical techniques to use when communicating with individuals in crisis in order to help calm them down and build their trust: • Look them in the eye • Use your name and call them by their name • Talk about something that distracts them from their delusions

Objectives • 2. ) Participants will be able to list three of the psychotic side effects that antibiotics are known to induce in healthy people who have no history of mental illness: • Delusional thinking • Religious obsession • Paranoia

Objectives • 3. ) Participants will be able to explain a specific safety measure that will equip them to protect their friends and family members from the dangerous side effects of prescription medications: • Carefully monitor the mental health of your friends or family members who are taking prescription medications

Questions? • Officer Bradley Colas VBPD 3 rd Precinct (C. O. P. Unit) 926 Independence Blvd Virginia Beach, VA 23455 607 -743 -3545 (cell) 757 -385 -2703 (work) bscolas@vbgov. com