Medical Student Research Programs at the UF College

Medical Student Research Programs at the UF College of Medicine Discovery Pathways Program Gregory Schultz, Ph. D Professor of Obstetrics & Gynecology schultzg@ufl. edu Scott Berceli, Ph. D Professor of Surgery and Bioengineering bercelis@ufl. edu Amanda Touchton Administrative Support amandatouchton@ufl. edu

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Ten-week immersive research experience in the summer break between MS 1/MS 2 Enrichment Program extending from MS 1 through the MS 2 years, designed to provide a deeper dive into various scholarly areas of interest

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Leader: Gravenstein, Blanka, Allen Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

QUESTION: Why should medical students participate in research & discovery during medical school? ANSWERS: § The practice of medicine is always advancing, which requires life-long learning from research literature – develops “critical thinking skills” § Contribute to the knowledge base of medicine § Improve competitiveness for top residency programs because many residency programs require research during training

Discovery Program An optional program for medical students to build a portfolio of accomplishment and scholarship in a defined topic areas. Goal: To promote development of expertise in areas of professional interest using a scholarly approach for research & discovery – Expose medical students to research and begin their training as Clinician Scientists – Allow students to perform an extended research project within the medical school curriculum – Improve problem solving and interpretive skills utilizing analytic methods – Increase communication skills – Develop teaching skills

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Leader: Gravenstein, Blanka, Allen Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

UF is a Research Powerhouse § Over $830 million of research at UF in 2018 – member of AAU § Clinical & Basic Science Research $350 million College of Medicine § Clinical & Translational Science Institute (CTSI) § Emerging Pathogens Institute (EPI) § Mc. Knight Brain Institute (National High Magnetic Field Lab) § Powell Gene Therapy Center § Biomedical Engineering

Summer MSRP Timeline • Faculty Mentors Post MSRP Project Ideas - September 2019 March 2021 • Students review MSRP Project Ideas and contact Faculty Mentors to discuss - September 2019 - March 2020 • Pre-Proposal forms open - November 2020 • Pre-Proposal Due- March 2021 • Final Proposal Due - April 2021 • Summer Research Project Begins - June 2021 • Enrichment Program begins - June 2021 • Mid-Summer Report Due – mid-July 2021 • Final Report Due – mid-August 2021 • Presentation of Research – COM Celebration of Research February 2022

Graduation with Honors in Research • A letter of nomination from the faculty mentor • A scholarly capstone product (a published paper, or a manuscript that is ready for submission to a scientific/medical journal) • A summary written by the medical student that describes his/her role in the research/discovery project 27 Honors in Research in class of 2020

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine Leader: Gravenstein, Blanka, Allen 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

Discovery Pathways Program Timeline • Year 1 • Select a Pathways track • Participate in track specific activities (seminars, “field trips”, etc. ) • Identify a mentor and develop a scholarly project • Summer Year 1/2 • 10 -weeks immersive scholarly experience • Academic course credit • Scholarship funds • Year 2 • Ongoing track specific activities • Complete scholarly project • Present poster of summer research in Annual Medical Student Research Day – continue R&D project

Discovery Pathways Program Timeline • Year 3 • Seminars, group meeting, reports • Year 4 • Research electives blocks – 2 x 4 weeks • Graduation with Honors in Research or Certificate of Distinction • Capstone work product – appropriate for Track (journal paper, policy, safety guideline, course content) • 17 Certificates of Distinction in class of 2020

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Leader: Gravenstein, Blanka, Allen Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

BUSINESS AND ENTREPRENEURSHIP IN MEDICINE (BEIM) Education BEIM provides a bridge for medical students to participate directly in medical innovation Innovation is a team effort – MD, MSe, MBA, JD etc Interdisciplina ry Teamwork Hands-On Experience Biomedical Engineering and Product Design Finance and Business Planning FDA Regulations Patents and Licensing The track provides education opportunities through seminars with experts in core innovation disciplines Use your knowledge to work with MDs, Ph. Ds, and engineering students on medical innovations Local Entrepreneurship

The UF Biomedical Engineering Department The UF Warrington Business School – Innovation and Entrepreneurship Center The UF Engineering Innovation Institute The UF Innovation Hub The UF Sid Martin Biotechnology Incubator Exactech Inc. • Gainesville/UF is a growing hub of biotech innovation • Through BEIM we maintain partnerships with local Gainesville/UF resources • Partnerships are a potential source of innovation projects for MD students INNOVATION CONNECTIONS It all started with Gatorade…

THE TRACK: CAPSTONE + SEMINARS Where will ideas come from? Seminar Series YOU, Shands Physician Innovators, local entrepreneurs Where will the manpower come from? Attend 75% of all seminars throughout the track: 5 -6 seminars per semester UF Engineering, BEIM Partnerships, and local resources Gainesville When can in I start? : As early as first semester (design into MSRP) or as late as MS 3 Semester II • Intro to Innovation Track • Intro to working with BME and • How to Build an Engineering the Engineering Design Process • Resources in Gainesville/ UF for innovation (Gator Hatchery) • How innovation at Shands works • Intellectual Property Protection team • MSRP and IRB: What are they and time to draft • Patent Law (OTL) • FDA Regulation (Engineering Innovation Institute) • Intro to starting a Business (Warrington) • Tour of UF Innovate Hub • Tour of Sid Martin Biotech Incubator https: //discovery. education. med. ufl. edu/business-and-innovation-in-medicine/ for more details • Ethics in Medical Engineering

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Leader: Gravenstein, Blanka, Allen Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

Track Leaders Health Outcomes and Policy Discovery Pathway with a strong emphasis on women and children’s health Melissa Bright, Ph. D Departments of Obstetrics and Gynecology & Pediatrics Mbright 08@ufl. edu Lindsay Thompson, MD MS Departments of Pediatrics and Health Outcomes and Biomedical Informatics Lathom@ufl. edu Meredith Mowitz, MD MS Department of Pediatrics mmowitz@ufl. edu

What works? Pathway Objectives For which patients or populations? Under what circumstances? Demonstrate foundational understanding of care concepts and methodologies used in health outcomes research Critically analyze peer-reviewed articles in the health outcomes and policy academic literature Formulate a research question or problem statement and use appropriate and rigorous methods to conduct a final project Present project at multiple venues using effective strategies for communication of science

Pathway Requirement s 1. Develop a learning contract in collaboration with a faculty mentor and course director that includes: 1. Project objectives 2. Action/research plan with timeline, outcomes, and assessment criteria 2. Complete steps in consultation with the faculty mentor and course director (includes MSRP, IRB training, contact hours in second year and possible 4 th year electives) 3. Submit and present final project

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Leader: Gravenstein, Blanka, Allen Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius T 32 Program Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

Local/Global Health Equity Discovery Track • Prioritizes improving health and achieving equity in health for all people worldwide. • Emphasizes transnational health issues, determinants, and solutions • Involves many disciplines within and beyond the health sciences • Promotes interdisciplinary collaboration • Synthesis of population-based prevention with individual-level clinical care. Global Defines the Problem Not the Location

Goal of LGHET prepare UF medical school graduates to understand health equity, work collaboratively in public or global health, and/or pursue a career of clinical service, research, teaching or policy

Structure of Track to Earn Distinction at Graduation: Meet 8 -10 Thursdays from 1 -3 for 3 semesters Example Topics: Social Determinants of Health Local and Global Health Infrastructures Health Equity Defined Health Literacy Immigrant and Migrant Health Nutrition and Water Sanitation and Health Field Trips Jail/Prison Tour Cooking Class Service Learning and Advocacy Complete service learning Learn how to become a true advocate for your patients Capstone Project Complete One Capstone Project in Local/Global Health Equity (to be completed through MSRP or in 4 th year) Questions? Elizabeth De. Vos MD, MPH Elizabeth. devos@jax. ufl. edu Meghan Nodurft-Froman MPH Meghan. froman@medicine. ufl. edu

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Leader: Gravenstein, Blanka, Allen Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius T 32 Program Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

MEDICAL EDUCATION TRACK LEADER: Lou Ann Cooper, Ph. D email: lacooper@ufl. edu visit: HMEB 447 DISCOVERY PATHWAYS

Examples of Student Projects Educational Research Comparison of Intended and Perceived Curricular Cultural Competence Content The Effects of Post-Discharge Phone Calls of Patients and Medical Students Survey Research Medical Student Usage of Third-Party Educational Videos Identifying Gaps and Inconsistencies in Urogynecologic Surgical Training of Obstetrics and Gynecology Residents Step 1 Parallel Curriculum: An Examination of the Use of External Resources Quality Improvement Program Development Peer Academic Enrichment Program Curriculum Development Enhancing Medical Student Education Through Low Cost Simulation Thinking Like a Scientist: Teaching for Cognitive Skills in a Classroom Setting Literature Review The Effects of Mindfulness Meditation on the Health and Well-Being of Medical Students: A Systematic Review

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Leader: Gravenstein, Blanka, Allen Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius T 32 Program Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

MEDICAL ETHICS AND LAW Presented by Professor Lauren Solberg

A MORE IN DEPTH LOOK AT ETHICAL AND LEGAL ISSUES IN CLINICAL CARE AND/OR RESEARCH… Selection of a track mentor • Professor Lauren Solberg (BLMP Program Director/faculty): lbsolberg@ufl. edu • Professor Bill Allen (BLMP faculty): wmallen@ufl. edu • Dr. Ray Moseley (BLMP faculty): rmoseley@ufl. edu Satisfactory completion of Research and Discovery (MS 1) Satisfactory completion of MSRP or other research project on relevant topic Satisfactory completion of Advanced Issues in Medical Ethics and Law elective as MS 3 or MS 4, or other elective with track permission AND…

*COMPLETE ANY 6 OF THE FOLLOWING ACTIVITIES… 1. Attend Florida Bioethics Network (FBN) conference or other relevant conference on bioethics, health law, etc: https: //fbn. miami. edu/conferences/index. html 2. Attend IRB or IACUC meeting 3. Attend IRB Brown Bag session 4. Attend ethics committee meeting 5. Participate in ethics consultation 6. Book reading and discussion (see book list on track site) 7. Complete online bioethics training program (e. g. CITI program on Human Subjects Protection) 8. Participate in other activities as approved by track mentor Examples: dept or college grand rounds, journal club, COM Office of Faculty Affairs and Professional Development seminar or workshop, meeting of other committee or workgroup *Each meeting/conference/workshop counts as 1 activity (e. g. 2 ethics committee meetings = 2 activities). May complete any combination from list.

ACTIVITY AND RESEARCH PROJECT EXAMPLES Students have participated in activities such as: Ethics committee meetings, ethics consultations Grand Rounds on topics including Baker Acts, Advance Care Planning for Patients Hospitalized for COVID 19 Webinar on Reproductive Justice and Contraception UF COM Special Event, Human Nature CRISPR Documentary Screening Research Project examples: Literature reviews Policy papers Data collection On topics such as physician-assisted suicide, informed consent, involuntary commitment laws (e. g. Baker Act)

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Leader: Gravenstein, Blanka, Allen Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius T 32 Program Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

Stoyan-Rosenzweigsociology, nstoyan@ufl. edu Social sciences. Nina - anthropology, Track leaders: Paulette Hahn Paulette. Hahn@medicine. ufl. edu psychology What are health humanities? Humanities- history, literature, classics, composition Arts- music, creative writing, theater, visual arts (painting, drawing, photography, printmaking), sculpture, film, etc. Used to: Understand experience of illness Understand human condition Enhance empathy and compassion Promote wellness Develop reflective skills Develop clinical skills Explore academic discussions

Develop familiarity with health humanities, academic literature and the medical humanities community Develop health humanities based teaching skills Understand role of humanities in reflective practice and wellness Explore application of humanities to patient-centered care Pathway Objectives Present/publish in the health humanities Define project in specific area of the humanities (Project may be part of the Summer MSRP or may be completed independent of MSRP) May have interdisciplinary collaboration with other Pathways http: //discovery. education. med. ufl. edu/research-track/discovery-tracks/medicalhumanities/

Activities- (didactic and experiential) Museum visits to enhance observational skills Nature walks and discussion of nature prescriptions Speakers and guest speakers on physician writing, medical anthropology, ethnomusicology, history of medicine, oral history Class writing and cartooning (creating graphic novels) What do we do? Projects and activities Projects Theater- use of plays on HIV/AIDS to promote empathy Film- creation of educational videos on HIV/AIDS risks History- research use of home remedies in American literature Literature- 19 th century poetry Arts- create displays of 1. photography 2. paintings for display in the Criser Cancer Resource Center Writing- review of physician literature, creation of essay on medical school experience Sculpture- creation of sculptural hands to assess student understanding of professionalism Survey physicians on attitudes toward patients with disabilities Production of films to assess student understanding of the patient story Literature review- studies of humanities-based intervention in the promotion of empathy

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Leader: Gravenstein, Blanka, Allen Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius T 32 Program Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

Quality and Patient Safety Discovery Pathway Carolyn K. Holland, MD, MEd, FACEP, FAAP Associate Professor – Emergency Medicine Physician Director of Quality – Emergency Med. Michele N. Lossius, MD, FAAP Professor – Pediatrics Chief Quality Officer – UF Health Division Chief – Pediatric Hospital Medicine

QPS Curriculum for all • Lectures in ICM/Health Policy, Preceptorship • Activities in CLG • 3 rd year Clerkship experiences • 4 th year Geriatrics Rotation

QI/PS Discovery Track • • Book Club Just Culture training Team. STEPPS Movie Nights

Capstone project • Participation in departmental and/or hospital wide activities • Longitudinal QI Team participatoin • QI Methodology workshops – Talk with those in the track for more details or contact Dr. Holland Dr. Lossius

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Leader: Gravenstein, Blanka, Allen Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius T 32 Program Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

Discovery Pathway on Promoting Resilience In Medicine Irene M. Estores, MD Irene. estores@medicine. ufl. edu https: //discovery. education. med. ufl. edu/discoverytracks/promoting-resilience-in-medicine-prime/

Description • Purpose: Introduce students to mind-body practices to enhance self-awareness and selfcare and promote resilience • 2 credit elective, offered in Spring Semester • 11 weeks of 2 -hour facilitated sessions • Meeting dates set to limit conflict with scheduled examinations • Optional 8 -week series of 1 -hour experiential sessions ( non-credit earning, scheduled the following summer or semester)

Course Material • Curriculum is based on the Mind-Body Skills Group at Year at the Georgetown University School of Medicine • Format: Opening meditation, check in, introduction of mind-body skill, experiential exercise, processing, closing meditation • Small group: 8 -10 students with the same faculty facilitators • Recommended readings and recorded audios for home practice on track site

Course Material • Student projects may include a compilation of essays, oral or poster presentation at a relevant local, regional or national conference or a publication Williams, M. K. , Estores, I. M. , & Merlo, L. J. (2020). Promoting Resilience in Medicine: The Effects of a Mind-Body Medicine Elective to Improve Medical Student Well-being. Global Advances in Health and Medicine. doi: 10. 1177/2164956120927367 • Students can participate in other MSRP projects even if enrolled in the PRIME Discovery track

Medical Student Discovery Program Medical Student Research Program (MSRP) Discovery Pathways Program Business and Innovation in Medicine 10 -week Immersive Research Experience in the summer break between MS 1/MS 2 Leader: Gravenstein, Blanka, Allen Local, Global Health Equity Track Leader: De. Vos, Nodurft-Froman Health Outcomes and Policy Track Leader: Thompson Medical Education Track Leader: Cooper Medical Ethics and Law Track Leader: Solberg Medical Humanities Track Leader: Stoyan-Rosenzweig, Hahn Patient Safety and Quality Track Leader: Holland, Lossius T 32 Program Biomedical, Clinical and Translational Research Leader: Islam Promoting Resilience in Medicine – PRIMe Leader: Estores, Cooke

Biomedical, Clinical and Translational Research Track The Nuts and Bolts Saleem Islam

Basic/Clinical Translational Track Goals • • Developing a project from a clinical question Engage existing Designing the data collection tools Data analysis techniques Understanding the analysis Creation of an abstract Presentation and publication

Tools • Your mentor • Epic – the EHR • REDCap – – https: //www. ctsi. ufl. edu/research/study-design-and-analysis/redcap/ • Brush up on stats • Medical writing

Summary • What is clinical research and its spectrum • Your goals • Achieve a project! • Tools