Major Cancer Milestones Major Cancer Milestones 1970 1979

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Major Cancer Milestones

Major Cancer Milestones

Major Cancer Milestones 1970– 1979

Major Cancer Milestones 1970– 1979

Major Cancer Milestones Early 1970 s: Increased use of radioactive ''seeds'' to target prostate

Major Cancer Milestones Early 1970 s: Increased use of radioactive ''seeds'' to target prostate and other cancers 1970– 1979

Major Cancer Milestones Late 1960 s–early 1970 s: Screening tests for colorectal cancer dramatically

Major Cancer Milestones Late 1960 s–early 1970 s: Screening tests for colorectal cancer dramatically reduce deaths 1971: National Cancer Act of 1971 becomes law 1971: More limited mastectomy proven effective for early-stage breast cancer 1970– 1979

Major Cancer Milestones 1970– 1979 1970 s: CT scanning provides clearer images of tumors,

Major Cancer Milestones 1970– 1979 1970 s: CT scanning provides clearer images of tumors, guiding radiation and other treatments

Major Cancer Milestones 1970– 1979 1970 s: Use of cancer-causing asbestos declines 1975– 1976:

Major Cancer Milestones 1970– 1979 1970 s: Use of cancer-causing asbestos declines 1975– 1976: First adjuvant chemotherapy increases cure rates for early-stage breast cancer

Major Cancer Milestones 1970– 1979 1977: New treatments cure men with testicular cancer 1977:

Major Cancer Milestones 1970– 1979 1977: New treatments cure men with testicular cancer 1977: Many women with breast cancer can opt for breast-conserving surgery Late 1970 s: Growing use of mammography saves lives

Major Cancer Milestones 1980– 1989

Major Cancer Milestones 1980– 1989

Major Cancer Milestones 1981: First cancer vaccine prevents cancer-causing hepatitis B infection 1980– 1989

Major Cancer Milestones 1981: First cancer vaccine prevents cancer-causing hepatitis B infection 1980– 1989

Major Cancer Milestones 1980– 1989 1982: Limited surgery helps rectal cancer patients avoid colostomies

Major Cancer Milestones 1980– 1989 1982: Limited surgery helps rectal cancer patients avoid colostomies

Major Cancer Milestones 1980– 1989 1986: PSA test enables early detection of prostate cancer

Major Cancer Milestones 1980– 1989 1986: PSA test enables early detection of prostate cancer 1986: Second-hand smoke formally declared a carcinogen 1986: Tamoxifen reduces breast cancer recurrence 1986: Global guidelines help ensure proper pain management

Major Cancer Milestones 1980– 1989 1985– 1991: Adjuvant therapy proven for colorectal cancer Late

Major Cancer Milestones 1980– 1989 1985– 1991: Adjuvant therapy proven for colorectal cancer Late 1980 s: Benzene discovered to cause blood cancers

Major Cancer Milestones 1980– 1989: Drugs to boost blood cells help patients finish cancer

Major Cancer Milestones 1980– 1989: Drugs to boost blood cells help patients finish cancer treatment, reduce infections

Major Cancer Milestones 1990– 1999

Major Cancer Milestones 1990– 1999

Major Cancer Milestones Early 1990 s: Laparoscopic surgery minimizes pain, recovery time for several

Major Cancer Milestones Early 1990 s: Laparoscopic surgery minimizes pain, recovery time for several cancers Early 1990 s: Shift to 3 -D radiation treatment plans increases precision, safety of therapy 1990– 1999

Major Cancer Milestones Early 1990 s: Cancer deaths begin steady decline 1991: Powerful anti-nausea

Major Cancer Milestones Early 1990 s: Cancer deaths begin steady decline 1991: Powerful anti-nausea drugs alleviate major side effect of cancer treatment 1990– 1999

Major Cancer Milestones 1990– 1999 1992: Sentinel lymph node biopsy determines cancer's spread with

Major Cancer Milestones 1990– 1999 1992: Sentinel lymph node biopsy determines cancer's spread with fewer side effects

Major Cancer Milestones 1990– 1999 1970 s– 1990 s: Melanoma linked to sun exposure

Major Cancer Milestones 1990– 1999 1970 s– 1990 s: Melanoma linked to sun exposure 1992– 1994: Taxanes emerge as a vital chemotherapy option for ovarian, breast cancer

Major Cancer Milestones 1990– 1999 1997: FDA approves first-ever targeted cancer drug, rituximab 1997:

Major Cancer Milestones 1990– 1999 1997: FDA approves first-ever targeted cancer drug, rituximab 1997: Surgery found to cure some patients with advanced colon cancer Late 1990 s: Prophylactic surgery helps prevent breast and ovarian cancers in women at high risk

Major Cancer Milestones 1990– 1999 Late 1990 s: New radiotherapy technique enables precise targeting

Major Cancer Milestones 1990– 1999 Late 1990 s: New radiotherapy technique enables precise targeting of tumors near sensitive tissue 1998: Drug therapy can reduce breast cancer risk in women at high risk 1998: Treatment guidelines highlight obesity-cancer link 1998: Chemotherapy before surgery helps more women benefit from breast-conserving treatment

Major Cancer Milestones 1990– 1999 1998, 2006: First targeted anti-breast cancer drug, trastuzumab (Herceptin),

Major Cancer Milestones 1990– 1999 1998, 2006: First targeted anti-breast cancer drug, trastuzumab (Herceptin), has major impact on care

Major Cancer Milestones 2000–Present

Major Cancer Milestones 2000–Present

Major Cancer Milestones 2000: Study links household radon exposure to lung cancer 2000–Present

Major Cancer Milestones 2000: Study links household radon exposure to lung cancer 2000–Present

Major Cancer Milestones 2000–Present 2001: New targeted therapy transforms treatment for rare leukemia 2001:

Major Cancer Milestones 2000–Present 2001: New targeted therapy transforms treatment for rare leukemia 2001: Imatinib found highly effective against rare gastrointestinal tumor

Major Cancer Milestones 2000–Present 1998– 2003: Doubling of U. S. biomedical research budget expands

Major Cancer Milestones 2000–Present 1998– 2003: Doubling of U. S. biomedical research budget expands cancer research

Major Cancer Milestones 2000–Present 2003: Scientists decode the human genome 2003: Obesity pinpointed as

Major Cancer Milestones 2000–Present 2003: Scientists decode the human genome 2003: Obesity pinpointed as cause of many cancer deaths 2003, 2004: First targeted drugs for lung cancer attack ''EGFR'' receptor

Major Cancer Milestones 2000–Present 2004: FDA approves first ''anti-angiogenic'' drug, bevacizumab 2004, 2006: Two

Major Cancer Milestones 2000–Present 2004: FDA approves first ''anti-angiogenic'' drug, bevacizumab 2004, 2006: Two targeted drugs approved for advanced colon cancer 2004– 2005: Adjuvant therapy proven effective in lung cancer

Major Cancer Milestones 2000–Present 2005: U. S. launches effort to map cancer genomes 2005:

Major Cancer Milestones 2000–Present 2005: U. S. launches effort to map cancer genomes 2005: Research sheds light on long-term health problems of cancer survivors

Major Cancer Milestones 2000–Present 2006: First vaccine approved to prevent cervical cancer

Major Cancer Milestones 2000–Present 2006: First vaccine approved to prevent cervical cancer

Major Cancer Milestones 2000–Present 2009, 2010: Major studies report conflicting results about benefits of

Major Cancer Milestones 2000–Present 2009, 2010: Major studies report conflicting results about benefits of PSA testing

Major Cancer Milestones 2000–Present 2010: CT scanning reduces lung cancer deaths among heavy smokers

Major Cancer Milestones 2000–Present 2010: CT scanning reduces lung cancer deaths among heavy smokers 2010: First drug shown to improve survival for patients with advanced melanoma 2010: Adding palliative care to standard chemotherapy improves survival for advanced lung cancer patients 2011: Record number of Americans surviving cancer – nearly 12 million

Major Cancer Milestones Five-Year Survival Source: National Cancer Institute

Major Cancer Milestones Five-Year Survival Source: National Cancer Institute

Major Cancer Milestones Source: National Cancer Institute Mortality

Major Cancer Milestones Source: National Cancer Institute Mortality

Major Cancer Milestones Source: National Cancer Institute New Cases

Major Cancer Milestones Source: National Cancer Institute New Cases

Visit Cancer. Progress. Net for an interactive timeline of progress against a range of

Visit Cancer. Progress. Net for an interactive timeline of progress against a range of common cancers Cancer. Progress. Net is a project of the American Society of Clinical Oncology, which represents nearly 30, 000 physicians who treat people with cancer and research new cures