M 220 Focusedultrasonicator User Training Adaptive Focused Acoustics
![M 220 Focused-ultrasonicator User Training M 220 Focused-ultrasonicator User Training](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-1.jpg)
![Adaptive Focused Acoustics® (AFA®) John Doe September 00, 2017 www. covaris. com Proprietary 2 Adaptive Focused Acoustics® (AFA®) John Doe September 00, 2017 www. covaris. com Proprietary 2](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-2.jpg)
![The Patented Covaris AFA® Attributes • AFA is the technology behind Covaris Focusedultrasonicators • The Patented Covaris AFA® Attributes • AFA is the technology behind Covaris Focusedultrasonicators •](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-3.jpg)
![How does ultrasonication work? Cavitation • • • Acoustic waves passing through a solution How does ultrasonication work? Cavitation • • • Acoustic waves passing through a solution](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-4.jpg)
![How does an acoustic treatment work? AFA treatments consist of very high-frequency acoustic signals How does an acoustic treatment work? AFA treatments consist of very high-frequency acoustic signals](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-5.jpg)
![How does an acoustic treatment work? Covaris electronics drive the transducer with a train How does an acoustic treatment work? Covaris electronics drive the transducer with a train](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-6.jpg)
![How does an acoustic treatment work? Nominal average power is the Peak Incident Power How does an acoustic treatment work? Nominal average power is the Peak Incident Power](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-7.jpg)
![M 220 Focused-ultrasonicator John Doe September 00, 2017 www. covaris. com Proprietary 8 M 220 Focused-ultrasonicator John Doe September 00, 2017 www. covaris. com Proprietary 8](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-8.jpg)
![M 220 - Overview Proprietary 9 M 220 - Overview Proprietary 9](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-9.jpg)
![System Attributes • • • Runs on Sono. Lab™ software Compact design (computer mount System Attributes • • • Runs on Sono. Lab™ software Compact design (computer mount](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-10.jpg)
![M 220 - Acoustics Sample Holder (Insert) Water Bath Housing Sensor Module Water Level M 220 - Acoustics Sample Holder (Insert) Water Bath Housing Sensor Module Water Level](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-11.jpg)
![M 220 Holder XTU and Inserts A single XTU holder will accommodate all 4 M 220 Holder XTU and Inserts A single XTU holder will accommodate all 4](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-12.jpg)
![M 220 Holder XTU, Insert, and Consumables M 220 Holder XTU Insert micro. TUBE M 220 Holder XTU, Insert, and Consumables M 220 Holder XTU Insert micro. TUBE](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-13.jpg)
![M 220 - Features Simple controls and start requirements Easy fill with AFA-grade water M 220 - Features Simple controls and start requirements Easy fill with AFA-grade water](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-14.jpg)
![M 220 – Water Temperature Control Proprietary 15 M 220 – Water Temperature Control Proprietary 15](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-15.jpg)
![M 220 – Preloaded Methods Proprietary 16 M 220 – Preloaded Methods Proprietary 16](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-16.jpg)
![micro. TUBEs for DNA Shearing Part Number Product Name Sample Volume Cap Fragment Size micro. TUBEs for DNA Shearing Part Number Product Name Sample Volume Cap Fragment Size](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-17.jpg)
![mini. TUBEs The Covaris mini. TUBE is optimized to reproducibly shear genomic DNA into mini. TUBEs The Covaris mini. TUBE is optimized to reproducibly shear genomic DNA into](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-18.jpg)
![tru. Ch. IP Consumable – Kits and Tubes Part Number Product Name Sample Volume tru. Ch. IP Consumable – Kits and Tubes Part Number Product Name Sample Volume](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-19.jpg)
![Validated Protocols for micro. TUBE 200 bp: PIP 50 W, DF 20%, cpb 200, Validated Protocols for micro. TUBE 200 bp: PIP 50 W, DF 20%, cpb 200,](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-20.jpg)
![Validated Protocols for micro. TUBE 200 bp: PIP 50 W, DF 20%, cpb 200, Validated Protocols for micro. TUBE 200 bp: PIP 50 W, DF 20%, cpb 200,](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-21.jpg)
![Validated Protocols for micro. TUBE 500 bp: PIP 50 W, DF 10%, cpb 200, Validated Protocols for micro. TUBE 500 bp: PIP 50 W, DF 10%, cpb 200,](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-22.jpg)
![Validated Protocols for micro. TUBE 1000 bp: PIP 50 W, DF 5%, cpb 200, Validated Protocols for micro. TUBE 1000 bp: PIP 50 W, DF 5%, cpb 200,](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-23.jpg)
![Setting up Samples in 15 µl Sample Tubes Why centrifugation ? • Dynamic DNA Setting up Samples in 15 µl Sample Tubes Why centrifugation ? • Dynamic DNA](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-24.jpg)
![Preparing the M 220 for Use • Turn on M 220 and start computer Preparing the M 220 for Use • Turn on M 220 and start computer](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-25.jpg)
![Preparing the M 220 for Use Draining water and cleaning • Special care needs Preparing the M 220 for Use Draining water and cleaning • Special care needs](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-26.jpg)
![Additional Applications • tru. Ch. IP® Chromatin Shearing Kits • • tru. XTRAC® FFPE Additional Applications • tru. Ch. IP® Chromatin Shearing Kits • • tru. XTRAC® FFPE](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-27.jpg)
![Contact – United States US HEADQUARTERS Covaris, Inc. 14 Gill Street, Unit H Woburn, Contact – United States US HEADQUARTERS Covaris, Inc. 14 Gill Street, Unit H Woburn,](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-28.jpg)
![Contact – International Europe, Middle East, and Africa Covaris, Ltd Unit 3, Brighton Office Contact – International Europe, Middle East, and Africa Covaris, Ltd Unit 3, Brighton Office](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-29.jpg)
- Slides: 29
![M 220 Focusedultrasonicator User Training M 220 Focused-ultrasonicator User Training](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-1.jpg)
M 220 Focused-ultrasonicator User Training
![Adaptive Focused Acoustics AFA John Doe September 00 2017 www covaris com Proprietary 2 Adaptive Focused Acoustics® (AFA®) John Doe September 00, 2017 www. covaris. com Proprietary 2](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-2.jpg)
Adaptive Focused Acoustics® (AFA®) John Doe September 00, 2017 www. covaris. com Proprietary 2
![The Patented Covaris AFA Attributes AFA is the technology behind Covaris Focusedultrasonicators The Patented Covaris AFA® Attributes • AFA is the technology behind Covaris Focusedultrasonicators •](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-3.jpg)
The Patented Covaris AFA® Attributes • AFA is the technology behind Covaris Focusedultrasonicators • Solid state 0. 5 MHz ultrasonic transducer • 3 mm wavelength ideal for processing biological molecules • Geometrically focused acoustic energy • Non-contact delivery of Controlled focused acoustic energy • Acoustically optimized sample vessel design • Consistent sample temperature Proprietary 3
![How does ultrasonication work Cavitation Acoustic waves passing through a solution How does ultrasonication work? Cavitation • • • Acoustic waves passing through a solution](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-4.jpg)
How does ultrasonication work? Cavitation • • • Acoustic waves passing through a solution cause localized pressure fluctuations The fluctuations cause dissolved gasses to form microscopic bubbles The bubbles grow, oscillate, and collapse These processes generate shear forces Covaris AFA technology enables precise control of the generated shear forces • Cumulative effect of hundred of thousands of cavitation bubbles Stroboscopic image of single collapsing 2 mm bubble @ 60 Hz Proprietary 4
![How does an acoustic treatment work AFA treatments consist of very highfrequency acoustic signals How does an acoustic treatment work? AFA treatments consist of very high-frequency acoustic signals](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-5.jpg)
How does an acoustic treatment work? AFA treatments consist of very high-frequency acoustic signals occurring in a series of “bursts” with each burst followed by a zero power state, as illustrated on the next slide. AFA Treatments are defined by the following parameters: • Cycles per Burst - the number of acoustic oscillations contained in each burst. The illustration on the next slide shows five cycles in each burst. • Duty Factor - the percentage of active burst time in the acoustic treatment. The illustration shows a Duty Factor of 20%. • Peak Incident Power - the instantaneous power, in Watts, driving the transducer during each burst. • Average Incident Power - Peak Incident Power multiplied by the Duty Factor. Proprietary 5
![How does an acoustic treatment work Covaris electronics drive the transducer with a train How does an acoustic treatment work? Covaris electronics drive the transducer with a train](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-6.jpg)
How does an acoustic treatment work? Covaris electronics drive the transducer with a train of electrical “bursts” (t 1) with amplitudes defined by Peak Incident Power (A). Each burst has a duration defined by “Cycles per Burst” and the ON time is defined by Duty Factor (t 1/t 2). Proprietary 6
![How does an acoustic treatment work Nominal average power is the Peak Incident Power How does an acoustic treatment work? Nominal average power is the Peak Incident Power](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-7.jpg)
How does an acoustic treatment work? Nominal average power is the Peak Incident Power multiplied by the Duty Factor. The shape and type of sample vessel, sample volume, water temperature and water quality influence actual power measured by the system and reported by Sono. Lab. Proprietary 7
![M 220 Focusedultrasonicator John Doe September 00 2017 www covaris com Proprietary 8 M 220 Focused-ultrasonicator John Doe September 00, 2017 www. covaris. com Proprietary 8](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-8.jpg)
M 220 Focused-ultrasonicator John Doe September 00, 2017 www. covaris. com Proprietary 8
![M 220 Overview Proprietary 9 M 220 - Overview Proprietary 9](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-9.jpg)
M 220 - Overview Proprietary 9
![System Attributes Runs on Sono Lab software Compact design computer mount System Attributes • • • Runs on Sono. Lab™ software Compact design (computer mount](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-10.jpg)
System Attributes • • • Runs on Sono. Lab™ software Compact design (computer mount on top of instrument) Low water volume (approximately 15 ml) Degassing not required Integrated temperature control – no external chiller required. All run parameters programmable via Sono. Lab software Proprietary 10
![M 220 Acoustics Sample Holder Insert Water Bath Housing Sensor Module Water Level M 220 - Acoustics Sample Holder (Insert) Water Bath Housing Sensor Module Water Level](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-11.jpg)
M 220 - Acoustics Sample Holder (Insert) Water Bath Housing Sensor Module Water Level Sensor Transducer 500 k. Hz Proprietary 11
![M 220 Holder XTU and Inserts A single XTU holder will accommodate all 4 M 220 Holder XTU and Inserts A single XTU holder will accommodate all 4](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-12.jpg)
M 220 Holder XTU and Inserts A single XTU holder will accommodate all 4 micro. TUBE inserts. M 220 Holder XTU Insert micro. TUBE 50 μl 500488 M 220 Holder XTU Insert micro. TUBE 130 μ 500489 M 220 Holder XTU Insert micro. TUBE 15 μl 500420 M 220 Holder XTU Insert micro. TUBE 500 μl 500471 M 220 Holder XTU 500414 Proprietary 12
![M 220 Holder XTU Insert and Consumables M 220 Holder XTU Insert micro TUBE M 220 Holder XTU, Insert, and Consumables M 220 Holder XTU Insert micro. TUBE](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-13.jpg)
M 220 Holder XTU, Insert, and Consumables M 220 Holder XTU Insert micro. TUBE 15 µl 500420 micro. TUBE-15 Beads Screw-cap 520145 milli. TUBE 1 ml 520128 M 220 Holder XTU Insert micro. TUBE 50 µl 500488 micro. TUBE-50 AFA Filter Screw-cap 520166 milli. TUBE 1 ml AFA Fiber 520130 M 220 Holder XTU Insert micro. TUBE 130 µl 500489 M 220 Holder XTU Insert micro. TUBE 500 µl 500471 M 220 Holder XTU 500414 M 220 Holder XTU Insert micro. TUBE 15 µl 500422 micro. TUBE-130 AFA Filter Screw-cap 520216 micro. TUBE AFA Fiber Crimp Cap 520045 micro. TUBE-500 AFA Fiber Screw-cap 520185 Proprietary 13
![M 220 Features Simple controls and start requirements Easy fill with AFAgrade water M 220 - Features Simple controls and start requirements Easy fill with AFA-grade water](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-14.jpg)
M 220 - Features Simple controls and start requirements Easy fill with AFA-grade water Proprietary 14
![M 220 Water Temperature Control Proprietary 15 M 220 – Water Temperature Control Proprietary 15](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-15.jpg)
M 220 – Water Temperature Control Proprietary 15
![M 220 Preloaded Methods Proprietary 16 M 220 – Preloaded Methods Proprietary 16](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-16.jpg)
M 220 – Preloaded Methods Proprietary 16
![micro TUBEs for DNA Shearing Part Number Product Name Sample Volume Cap Fragment Size micro. TUBEs for DNA Shearing Part Number Product Name Sample Volume Cap Fragment Size](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-17.jpg)
micro. TUBEs for DNA Shearing Part Number Product Name Sample Volume Cap Fragment Size Beads/Fiber 520145 (25) 520153 (250) microtube-15 AFA Beads Screw-Cap 15 to 20 µl, +/- 1 µl Screw-Cap 100 bp - 1. 5 kb Beads 520166 (25) 520167 (250) micro. TUBE-50 AFA Fiber Screw-Cap 55 µl, +/- 2. 5 µl Screw-Cap 100 bp - 1. 5 kb Fiber 520216 (25) micro. TUBE-130 AFA Fiber Screw-Cap 130 µl, +/- 5 µl Screw-Cap 100 bp - 1. 5 kb Fiber 520185 (25) micro. TUBE-500 AFA Fiber Screw-Cap 320 µl, +/- 10 µl 500 µl, +/- 10 µl Screw-Cap 100 bp - 1. 5 kb Fiber Proprietary 17
![mini TUBEs The Covaris mini TUBE is optimized to reproducibly shear genomic DNA into mini. TUBEs The Covaris mini. TUBE is optimized to reproducibly shear genomic DNA into](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-18.jpg)
mini. TUBEs The Covaris mini. TUBE is optimized to reproducibly shear genomic DNA into fragments ranging from 2 to 5 kb in size. Fragment distributions are tight and precisely centered on the targeted size with three available classes of mini. TUBEs. • Dynamic DNA mass range of 1 µg to 10 µg • Mate Pair libraries • Raindance library prep Clear mini. TUBE 520064 Fragments centered on 2 kb Blue mini. TUBE 520064 520065 Fragments centered on 3 kb Red mini. TUBE 520066 Fragments centered on 4 kb Use M 220 holder P/N 500302 for mini. TUBEs Proprietary 18
![tru Ch IP Consumable Kits and Tubes Part Number Product Name Sample Volume tru. Ch. IP Consumable – Kits and Tubes Part Number Product Name Sample Volume](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-19.jpg)
tru. Ch. IP Consumable – Kits and Tubes Part Number Product Name Sample Volume 520083 (25) tru. Ch. IP Chromatin Shearing Kit Tissue SDS • Includes low tissue mass optimized protocol for processing up to 20 mg of tissue in 130 µl shearing volume • Includes high tissue mass optimized protocol for processing up to 120 mg of tissue in 1 ml shearing volume 520154 520155 (250) tru. Ch. IP Chromatin Shearing Reagent Kit with Formaldehyde • Includes low-cell protocol optimized for processing 0. 5 -3 million cells in 130 µl shearing volume • Includes high-cell protocol optimized for processing 5 -30 million cells in 1 ml shearing volume 520156 tru. Ch. IP Ultra-low Chromatin with Formaldehyde • Optimized for processing ≤ 100 K cells Part Number Product Name Sample Volume Cap Fragment Size Beads/Fiber micro. TUBE-130 AFA Fiber Screw-Cap 130 µl, +/- 5 µl Screw-Cap 100 bp - 1. 5 kb fiber 520128 (100) 520129 (1000) milli. TUBE 1 ml Screw-Cap 200 -700 None 520130 (100) 520131 (1000) milli. TUBE 1 ml AFA Fiber 1 ml Screw-Cap n/a Fiber 520216 (25) Proprietary 19
![Validated Protocols for micro TUBE 200 bp PIP 50 W DF 20 cpb 200 Validated Protocols for micro. TUBE 200 bp: PIP 50 W, DF 20%, cpb 200,](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-20.jpg)
Validated Protocols for micro. TUBE 200 bp: PIP 50 W, DF 20%, cpb 200, time 160 sec, temp 20ºC Average 202 bp Std Dev 4. 3 bp CV 2. 1% Proprietary 20
![Validated Protocols for micro TUBE 200 bp PIP 50 W DF 20 cpb 200 Validated Protocols for micro. TUBE 200 bp: PIP 50 W, DF 20%, cpb 200,](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-21.jpg)
Validated Protocols for micro. TUBE 200 bp: PIP 50 W, DF 20%, cpb 200, time 160 sec, temp 20ºC Average 296 bp Std Dev 6. 4 bp CV 2. 2% Proprietary 21
![Validated Protocols for micro TUBE 500 bp PIP 50 W DF 10 cpb 200 Validated Protocols for micro. TUBE 500 bp: PIP 50 W, DF 10%, cpb 200,](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-22.jpg)
Validated Protocols for micro. TUBE 500 bp: PIP 50 W, DF 10%, cpb 200, time 60 sec, temp 20ºC Average 496 bp Std Dev 21. 7 bp CV 4. 4% Proprietary 22
![Validated Protocols for micro TUBE 1000 bp PIP 50 W DF 5 cpb 200 Validated Protocols for micro. TUBE 1000 bp: PIP 50 W, DF 5%, cpb 200,](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-23.jpg)
Validated Protocols for micro. TUBE 1000 bp: PIP 50 W, DF 5%, cpb 200, time 60 sec, temp 20º C Average 1023 bp Std Dev 66. 3 bp CV 6. 5% Proprietary 23
![Setting up Samples in 15 µl Sample Tubes Why centrifugation Dynamic DNA Setting up Samples in 15 µl Sample Tubes Why centrifugation ? • Dynamic DNA](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-24.jpg)
Setting up Samples in 15 µl Sample Tubes Why centrifugation ? • Dynamic DNA mass range of 1 µg to 10 µg • Mate Pair libraries • Raindance library prep Proprietary 24
![Preparing the M 220 for Use Turn on M 220 and start computer Preparing the M 220 for Use • Turn on M 220 and start computer](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-25.jpg)
Preparing the M 220 for Use • Turn on M 220 and start computer • Open Sono. Lab software • Fill water bath with the XTU holder in place with AFA-grade water • Ensure Water Level is within specified operating levels • Select a Method in the Method box - this will set the run parameters • Protocol will initiate once the water temperature reaches specified range • Load sample vessel into the XTU tube holder and slide the weight into the running position • Close the safety enclosure door • Select Run Proprietary 25
![Preparing the M 220 for Use Draining water and cleaning Special care needs Preparing the M 220 for Use Draining water and cleaning • Special care needs](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-26.jpg)
Preparing the M 220 for Use Draining water and cleaning • Special care needs to be taken when draining the water from water bath. • Remove the tube holder and place it on a clean, dry surface. Draw the water from the acoustic assembly using the provided syringe. It is important to use the plastic tip on the syringe to prevent the scratch of the transducer surface. Water needs to be drawn as completely as possible. • Use the disposable cleaning swab to sweep the water channels in the Acoustic Assembly. Wipe the surfaces of the transducer and the metal housing with lint-free cloth and air dry for next use. • Store the Tube Holder Insert in a dry place Shutdown Procedure • If the instrument will be idle for an extended time (e. g. overnight or a weekend), shut down the instrument using the following procedure: Empty the water bath, store the Tube Holder Insert in a dry place. Proprietary 26
![Additional Applications tru Ch IP Chromatin Shearing Kits tru XTRAC FFPE Additional Applications • tru. Ch. IP® Chromatin Shearing Kits • • tru. XTRAC® FFPE](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-27.jpg)
Additional Applications • tru. Ch. IP® Chromatin Shearing Kits • • tru. XTRAC® FFPE t. NA, DNA, and RNA Kits • • Sample Prep for Mycobacterium spp. Protein Extraction Buffers • • Single-tube blood collection, stabilization, transport, and biomarker extraction solution tru. XTRAC MALDI-TOF • • Improved DNA yields from Dried Blood Spots tru. COLLECT™ • • NGS-grade RNA and DNA Extraction from FFPE tissues tru. XTRAC DBS • • Optimized reagents and protocols for chromatin shearing with AFA Focused-ultrasonicators A range of extraction buffers for the efficient protein extraction from cells and tissues optimized for your downstream application DNA Shearing Verification Kit • Verify the performance of your AFA Focused-ultrasonicators with the DNA Shearing Verification Kit Proprietary 27
![Contact United States US HEADQUARTERS Covaris Inc 14 Gill Street Unit H Woburn Contact – United States US HEADQUARTERS Covaris, Inc. 14 Gill Street, Unit H Woburn,](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-28.jpg)
Contact – United States US HEADQUARTERS Covaris, Inc. 14 Gill Street, Unit H Woburn, Massachusetts 01801 -1721 USA Tel: +1 781 -932 -3959 Fax: +1 781 -932 -8705 www. covaris. com If you need further assistance our staff of Application Scientists, Engineers, and Technical Specialists are committed to providing you with prompt and professional support. For service and support for your Covaris instruments and consumables in the US or Europe, contact: Tech. Support@covaris. com For Application Support in the US or Europe, contact: Application. Support@covaris. com. To Place Orders in the US, contact: Customer. Service@covaris. com. Proprietary 28
![Contact International Europe Middle East and Africa Covaris Ltd Unit 3 Brighton Office Contact – International Europe, Middle East, and Africa Covaris, Ltd Unit 3, Brighton Office](https://slidetodoc.com/presentation_image_h/f734d9a0dcd890daf8b932f862298312/image-29.jpg)
Contact – International Europe, Middle East, and Africa Covaris, Ltd Unit 3, Brighton Office Campus Hunns Mere Way Woodingdean Brighton BN 2 6 AH United Kingdom Tel: +44 (0)845 872 0100 Fax: +44 (0) 845 384 9160 To Place Orders in Europe, contact: EMEACustomer. Service@covaris. com www. covaris. com International Our international distributors provide Covaris products to laboratories around the world. For information about international product distribution opportunities, please contact International. Sales@covaris. com Proprietary 29
Afa grade water
Adaptive focused acoustics
Site:slidetodoc.com
Chichen itza ball court acoustics
Room acoustics design criteria
Hoorzaken
Acoustics
Acoustics
Lecture hall acoustics
Engineering acoustics
Wilson acoustics limited
Sound waves meaning
Acoustics graduate programs
Fundamentals of acoustics
Pinna acoustics
Jd acoustics
Peters uncertainty in acoustics (epub|pdf|mobi)
Pinna acoustics
Single user and multiple user operating system
Operating systems
Erp user training
End user training best practices
Joint legacy
Problem-focused coping examples
Htc grid mammography
Focused and unfocused tasks examples
Process focused
Product oriented layout example
Nutrition focused physical exam
Problem-focused coping examples