Lymphatic System 1 Lymphatic System Functions Return fluid
- Slides: 19
Lymphatic System 1
Lymphatic System • • Functions Return fluid to general circulation Production of WBCs Immunity 2
Lymphatic Vessels • Open circulatory system • Originate blindly in tissue interstices throughout the body except CNS and those without blood supply • Thin walled - endothelium only • Permeable 3
Lymphatic Vessels 4
Lymphatic Vessels • Parallel venous flow • Asymmetrical distribution • Two major junctions with cardiovascular system – Thoracic duct into left subclavian vein – Right lymphatic duct into right subclavian vein 5
Ducts 6
Lymphatic Vessels 7
Lymphatic Physiology • Movement into lymphatic capillaries function of osmotic pressure • Valves and muscular activity assist return flow 8
Lymphatic Organs • • • Lymph nodes Spleen Tonsils Thymus Diffuse tissue 9
Lymph Nodes • • Distributed along vascular pathway Filter lymph Encapsulated by dense CT stroma/framework of reticular fibers, trabeculae • Parenchyma of cortex and medulla • Lymphocytes/t cells 10
Lymph Nodes 11
Lymph Nodes • • Macrophages B lymphocytes/b cells Multiple afferent lymphatics Usually a single efferent exiting at hilus/hilum • Size variable 1 -25 mm, change with infection • Secondary tumor sites via metastasis 12
Spleen • • • Functions Fetal blood development Store and release blood during stress Recycle old blood cells B cell maturation into plasma cells 13
Spleen Structure • 12 cm oval body in left hypochondriac region • Splenic artery and vein enter at hilus • Covered with peritoneum • Structure similar to lymph node • Parenchyma of two types 14
Spleen Structure • • • Red pulp Blood filled venous sinuses Splenic cords/Billroth’s cords White pulp Lymphocyte production 15
Tonsils • Aggregated lymph nodes • Concentrated in Waldeyer’s tonsilar ring – Lingual – Palatine – Pharyngeal/adenoid 16
Thymus • • • In superior mediastinum Two lobes Surrounded by CT capsule Cortex = reticular fibers + lymphocytes Medulla - epithelial cells produce thymosin stimulating maturation of T cells, form Hassall’s corpuscles • Maximum size 10 -12 yrs old ~ 40 grams, degenerates with age 17
Diffuse Lymphatic Tissue • Not encapsulated • Widely distributed throughout body • Found in lamina propria of digestive tract, respiratory, urinary and reproductive systems 18
Pathology • Lymphangitis • Lymphadenopathy • Edema 19
- Lymphatic system
- Lymphatic system
- Largest lymphoid organ
- Fluid sf
- P1-p2
- Fluid statics deals with
- Total body water
- Interstitial fluid vs extracellular fluid
- Hypoosmotic
- Fluid mechanics chapter
- Movement of body fluids
- What is perihepatic ascites
- Lymphatic system vs endocrine system
- Saphenous vein medial malleolus
- What are the function of lymphatic system
- Chapter 12 the lymphatic system and body defenses
- Its tubular dude
- Structures of the lymphatic system
- Chapter 22 lymphatic system and immunity
- Chapter 10 lymphatic system diseases and disorders