Longitudinal Association of Telomere Attrition with the Effects

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Longitudinal Association of Telomere Attrition with the Effects of Antihypertensive Treatment and Blood Pressure

Longitudinal Association of Telomere Attrition with the Effects of Antihypertensive Treatment and Blood Pressure Lowering Shuyuan Zhang, Rongxia Li, Yunyun Yang, Yu Chen, Shujun Yang, Jian Li, Cunjin Wu, Tao Kong, Tianlong Liu, Jun Cai, Li Fu, Yanan Zhao, Rutai Hui, Weili Zhang 1 State Key Laboratory of Cardiovascular Disease, Fu. Wai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College &#x 00026; Chinese Academy of Medical Sciences, Beijing, China 2 The Second Hospital of Tianjin Medical University, Tianjin, China 3 Hypertension Centre, Fu. Wai Hospital, National Center for Cardiovascular Diseases, Peking Union Medical College &#x 00026; Chinese Academy of Medical Sciences, Beijing, China 4 Benxi Railway Hospital, Liaoning, China Fig 2. Differences of blood pressure lowering between the lengthen and the shorten groups during 2014 -2016. Abbreviations: SBP, systolic blood pressure; PP, pulse pressure. &#x 0002 A; P &#x 0003 C; 0. 05, &#x 0002 A; P &#x 0003 C; 0. 01. P values and adjusted mean were calculated by generalized linear model adjustment for covariates including age, gender (except in gender-strati&#x 0 FB 01; ed analysis), smoking DOI: 10. 14336/AD. 2019. 0721 status, alcohol intake, medical history, the stage of baseline blood pressures, baseline telomere length, and changes in BMI, waist-to-hip, fasting glucose, TC, triglycerides, HDL-C, and LDL-C from 2014 to 2016. Error bars indicate 95&#x 00025; CI.