LICEO SCIENTIFICO FRANCESCO REDI Liver cancer Riccardo Castiglia

LICEO SCIENTIFICO FRANCESCO REDI Liver cancer Riccardo Castiglia Prof. ssa Vannuccini

LIVER STRUCTURE Principal components PORTAL VEIN HEPATIC ARTERY HEPATIC LOBUL

LIVER FUNCTIONS � Production of bile � Production of enzymes � Metabolis functios(glucogenesis, gliconelosis, glicogenosintesis) � Protein metabolism � Synthesis of cholesterol and tryglyceridis � Detoxification

LIVER CANCER (EPATOCARCINOMA) PRIMARY (PRIMITIVO) MALICIOUS SECONDARY This comes from HEPATOCARCINOMACOLANGIOCARCINOMA metastases BENIGN HEMANGIOMA SIMPLE ADENOMA

SPREAD WORLDWIDE The liver cancer rapresents the third principal cause of tumor death, after lugs and stomach cancer WEST AFRICA EAST 5 people on 100’ 000 meet liver cancer 110 people on 100’ 000 meet liver cancer, especially in Mozambigo 30 people on 100’ 000 meet liver cancer

CAUSES 10% 60% hepatitis cirrhosis 25% viral hepatitis 10% hemacromatosis 5% Sex ; age; heredity; alcool; smoke; drugs 5% 60%

SYMPTOMS HEPATOMEGAL Y ADDOMINAL PAIN (liver enlarged) (it often results in peritonitis) JAUNDICE (yellowing coloration of the skin) SPLEEN ENLARGED CIRROSIS (it often causes weight loss and fever) ASCITES

TREATEMET Surgery ( successefull of 25%) Liver transplantation(successefull of 24%) Chemioterapy (successefull of 35%) Interior residential treatments (successefull of 15 %) Chemioembolization (successefull of 14%) SURVIVAL Percentage taken from AIOM (italian associatio of medical oncology) In Italy: the 17% of men and 16% of women, that have met that neoplasms, are still in life after 5 years from the diagnosis

GRAZIE P ER L’ATTENZ IONE !!!!!