Lesson 6 Textbooks Repro Page 8 9 of

Lesson 6

� Textbooks � Repro �Page 8 -9 of ppq �Comparison sheet

� To know about fibrous proteins � Explain the term quaternary structure � Describe the properties and functions of fibrous proteins �Including collagen, keratin & elastin

� Draw the structure of a protein and label it in as much detail as you can

- Explain the term quaternary structure � Proteins made of more than one polypeptide chain � May have an inorganic component � Can’t function without all components �E. g. Haemoglobin and collagen

- Describe the properties and functions of fibrous proteins � 3 polypeptides � Wound together �Rope like structure �Triple helix �Hydrogen bonded � Flexible � Every 3 rd amino acid is glycine �Small �Closely � High packed when wound together amounts of proline and hydroxyproline �Repel each other, adding stability

- Describe the properties and functions of fibrous proteins � Complete the table using page 104 -105 in the book and your flipped learning

- Describe the properties and functions of fibrous proteins Feature Type of biological molecule Type of protein Protein Fibrous Main function Strength Carry oxygen Inorganic component No Haem group (Iron) Amino acid sequence Every 3 rd amino acid is glycine (small) High amounts of proline and hydroxyproline Only 1 type of polypeptide chain Microfibrils Connective tissue Variable Structure Where found in the body Collagen Haemoglobin Protein Globular 2 types of polypeptide chains Red blood cells

- Describe the properties and functions of fibrous proteins � Found in hair, skin & nails � Large amounts of cysteine �Lots of strong disulfide bonds �Less disulfide bonds means more flexible

- Describe the properties and functions of fibrous proteins � Found �E. g. in elastic fibres walls of blood vessels � Lots of soluble tropelastin molecules cross linked �To create large, stable, insoluble molecule �Can stretch and relax � Have alternating areas of hydrophobic and lysinerich �Cross links caused by hydrophobic interactions and covalent bonds involving lysine

� Past �Q 3 Paper Questions Jan 2008

� Past paper question Jan 11 Q 7

� Draw the structure of a protein and label it in as much detail as you can

� Complete the summary table