Lab 5 ALS Trigeminal System ALS ALS AN

Lab 5 - ALS, Trigeminal System

ALS

ALS AN OVERVIEW OF THE ANTEROLATERAL SY FOR PAIN AND TEMPERATURE SENSATION Note Cell body locations: Primary sensory afferent cell bodies DRG all levels of the spinal cord Primary Fast fibers – Ad fibers intense sharp pain Slow Fibers – C fibers dull throbbing, burning pain Central Processes enter via lateral aspect of dorsal roots Ventral white commisure

Haines 5 -1 Lissauers tract in dorsal horn Lamina 1+5 = projection neurons pain and temp. Lamina 2+3 = Substantia gelatinosa -receives afferents ALS Sacral Level Ventral White Commisure

Haines 5 -2 Lissauers tract in dorsal horn Lamina 1+5 = projection neurons pain and temp. Lamina 2+3 = Substantia gelatinosa -receives afferents ALS Lumbar Level Ventral White Commisure

Haines 5 -3 Lissauers tract in dorsal horn Lamina 5 = projection neurons pain and temp. Lamina 1+2 ALS Thoracic Level Ventral White Commisure

Haines 5 -4 Lissauers tract in dorsal horn Lamina 5 = projection neurons pain and temp. Lamina 2 Substantia gelatinosa -receives afferents ALS C 7 Level Ventral White Commisure

Haines 5 -5 Lissauers tract in dorsal horn Lamina 5 = projection neurons pain and temp. Substantia gelatinosa -receives afferents ALS C 1 Level Ventral White Commisure

Tegmentum = Reticular Formation + Periventricular Zone Haines 5 -9 Keep in Mind that the reticular formation is a poorly defined area. ALS Fast Fibers Caudal Medulla Level

Haines 5 -11 Reticular Formation – receives slow ALS fibers that take Multisynaptic course ALS Fast fiber Midrostral Medulla Level

Haines 5 -12 Reticular Formation – receives slow ALS fibers that take Multisynaptic course ALS Fast fiber Rostral Medulla Level Raphe Nucleus – Decending Pain Block (Serotonin or Nor. Ep)

Haines 5 -17 Reticular Formation – receives slow ALS fibers that take Multisynaptic course ALS Fast fiber Rostral Medulla Level Raphe Nucleus – Decending Pain Block (Serotonin or Nor. Ep)

Haines 5 -19 Reticular Formation – receives slow ALS fibers that take Multisynaptic course ALS Fast fiber Rostral Pons Level Raphe Nucleus – Decending Pain Block (Serotonin or Nor. Ep)

Haines 5 -20 Reticular Formation – receives slow ALS fibers that take Multisynaptic course ALS Fast fibers Medial Lemniscus Rostral Pons Level

Haines 5 -22 Periaqueductal Gray – receives fibers from ALS, and sends decending fibers to the Raphe Nucleus Reticular Formation – receives slow ALS fibers that take Multisynaptic course ALS Fast fibers Pons/midbrain jctn Level

Periaqueductal Gray – receives fibers from ALS, and sends decending fibers to the Raphe Nucleus Haines 5 -25 Reticular Formation – receives slow ALS fibers that take Multisynaptic course ALS Fast Fibers Rostral Midbrain Level

Haines 5 -30 Contains fibers from both: ALS and Medial Lemniscus Thalmus

Haines 5 -31 Slow Tract Receives pain and temp fibers from reticular formation and sends axons to different areas of the cortex.

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Black Board 33 Posterior limb of internal capsule

Trigeminal System

Tigeminal System (CN 5) (1) VTTT unconscious proprioceptors (2) Note: Fibers cross the midline (3) Trigeminal nuclear Complex

Haines 5 -8 Spinaltrigeminal Nucleus Spinaltrigeminal tract – ipsilateral pain and temp from face and teeth Caudal Medulla

Haines 5 -9 Spinaltrigeminal Nucleus – sends axons that cross at accend to VPM Spinaltrigeminal tract – ipsilateral pain and temp from face and teeth Caudal Medulla Level

Haines 5 -11 Spinaltrigeminal Nucleus Spinaltrigeminal tract – ipsilateral pain and temp from face and teeth Midrostral Medulla Level Axons cross and ascend in to VTTT at the caudal pons and continue to the VPM

Haines 5 -12 Spinaltrigeminal Nucleus Spinaltrigeminal tract Rostral Medulla Level

Haines 5 -17 Spinaltrigeminal Nucleus Spinaltrigeminal tract Rostral Medulla Level

Trigeminal Roots Haines 5 -19 Main Motor Nucleus Supplies muscles of mastication Main Sensory Nucleus Discriminative touch Receives fibes from trigem ganglion Sends axons across midline to VTTT Mixed Rostral Pons Level VTTT Contralateral spinotrgeminal tract (Ipsilateral)

Haines 5 -25 VTTT Contralateral Rostral Midbrain Level

Haines 5 -30 Posteror Limb of Internal Capsule Thalmus VPM = sensory relay nucleus for general face sensation and for taste

Haines 2 -11