Keywords Tissue engineering engineering design entrepreneurship Tissue Engineering

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Keywords: Tissue engineering, engineering design, entrepreneurship, Tissue Engineering Startup Simulator: Integrating Entrepreneurship into Tissue

Keywords: Tissue engineering, engineering design, entrepreneurship, Tissue Engineering Startup Simulator: Integrating Entrepreneurship into Tissue Engineering Education Scott A. Sell, Ph. D. Saint Louis University

Why? What problem are you solving? • The tissue engineering sector has an extremely

Why? What problem are you solving? • The tissue engineering sector has an extremely high percentage of startup companies funded by venture capital. However, students focusing in tissue engineering / biomaterials typically are not exposed to courses that teach or focus on entrepreneurship. What are your educational objectives? • Instill an entrepreneurial mindset into students taking BME 4410 Tissue Engineering • Educate and promote entrepreneurship skills relevant to the field • Teach students how to apply the practice of engineering design to a non-traditional engineering course

When? What is the developmental history of your innovation? • Dr. Scott Sell has

When? What is the developmental history of your innovation? • Dr. Scott Sell has worked on the integration of entrepreneurial concepts into BME 4410 since Spring 2015 • This work has been funded by both the KEEN and Coleman Fellows foundations to promote active collaborative learning, problem-based learning, and entrepreneurial-minded learning

Where? • Saint Louis University BME 4410: Tissue Engineering • While I have experience

Where? • Saint Louis University BME 4410: Tissue Engineering • While I have experience integrating this approach into only this particular course, the modules created have been disseminated to the other KEEN and Coleman Fellows institutions

What? • The semester long course is run from the perspective of student groups

What? • The semester long course is run from the perspective of student groups operating as individual tissue engineering startup companies competing for funding from a venture capitalist group. – This involves a number of ACL, PBL, and EML activities interspersed with traditional tissue engineering lecture materials throughout the semester – Topics covering intellectual property rights, market analysis, and pitching are covered (i. e. What is an NDA? ; How do we navigate the FDA? ; How do we create a business model canvas? ; etc. ) – Student design groups must research and present on three topical areas pertaining to their chosen tissue target for product development: • Market Analysis: describe the market for their tissue, competing products, failed products, etc. • Testing Regime: describe what testing will need to be done to create a successful product for this tissue (i. e. in vitro, mechanical testing, animal models, etc. ) • Novel Design/Approach: describe novel design, justify rationale for that design, address manufacturability, scale up and implementation, etc. – Each group presentation is judged by a three person panel consisting of myself and external entrepreneurs who are knowledgeable in the field – Painstorming: following each presentation, groups discuss possible drawbacks to each design and areas for possible improvement.

Prognosis? • Overall the students thoroughly enjoyed all of the ACL activities and were

Prognosis? • Overall the students thoroughly enjoyed all of the ACL activities and were very engaged in them • Students do a very good job of determining potential markets for their specific tissues and with determining ethical concerns for their tissues • Based upon student assessments: – The product design approach helped to learn about different tissues, fabrication techniques, and implementation strategies – Students tend to struggle with the “testing regime” phase – Painstorming helped with revising initial ideas for design (students actually wanted more painstorming surprisingly) – Ethical discussions/implications of products was one of their favorite activities – The role of the external entrepreneurs is invaluable. Their presence and input helps to legitimize the work in the mind of the students • Assessment is always an issue! I would love insight into how to best assess student learning, their inherent curiosity, and long-term impact on their entrepreneurial mindset.