Juvenile Macular Degeneration Lauran Maestas Meghan Raney Cressie

Juvenile Macular Degeneration Lauran Maestas Meghan Raney Cressie Wright

o Three major forms of Juvenile Macular Degeneration n Best’s Disease Juvenile Retinoschisis Stargardt Disease All are rare and cause central vision loss

Stargardt Disease o o First report in 1901 German Ophthalmologist Karl Stargardt 1997 genetic component discovered n n Recessive gene Both parents must have

Stargardt Gene Normal o Gene produces protein o Protein produces energy o Energy sent to the photoreceptor cells Stargardt o No protein produced o Without protein no energy o No energy photoreceptor cells in retina degenerates

Effects of gene defect o Fatty yellow pigment (Lipofusion) n n n Build up under cells in macula Rods and Cones are affected Atrophy in the macula Loss of central vision Blindness

Symptoms o Visual Acuity n 20/40 20/200 n Central Vision Loss n Vision Acuity n Blurry Vision n Distorted Vision

Symptoms n n n Dark Areas Color Perceptions Central Scotoma (Blind Spot in Central Vision) Night Blindness Photophobia (Abnormal tolerance for light)

Treatments o o No Cure Current research: n n n UV Protective glasses may slow the progression Limit intake of vitamin A Stem cells in adult body fat

References o Stargardt Disease. (n. d. ). American Macular Degeneration Foundation |. Retrieved July 11, 2014, from https: //www. macular. org/stargardt-disease o Stargardt macular degeneration. (2014, July 7). Genetics Home Reference. Retrieved July 11, 2014, from http: //ghr. nlm. nih. gov/condition/stargardt-macular-degeneration o Kinkade, D. R. (2012, November 6). Low Vision Eyeglasses Low. Vision. Eyeglasses. com: Guide to Macular Degeneration: Short Answers to Complex Questions. Retrieved July 11, 2014, from http: //lowvisioneyeglasses. blogspot. com/2012/11/guide-to-macular-degeneration-short. html o Stargardt Disease. (2014, November 7). . Retrieved July 11, 2014, from http: //www. retina-international. org/eyeconditions/retinal-degenerative-conditions/stargardt o Grossman, M. (2013, August 28). Stem Cells Discovered in Fat May Treat Macular Disgeneration, Retinitis Pigmentosa, Stargardt's. Eye conditions, eye care & diseases, treatment solutions. Retrieved July 11, 2014, from http: //www. naturaleyecare. com/blog/stem-cells-fat/ o Grossman, M. (n. d. ). Stargardt's Disease. Eye Care. Retrieved July 11, 2014, from http: //www. naturaleyecare. com/eyeconditions/stargardts/

Age-Related Macular Degeneration (AMD) Lauran Maestas Meghan Raney Cressie Wright

What is Age-Related Macular Degeneration (AMD)? q AMD is a condition that causes central vision loss AMD is the leading cause of vision loss for people over the age of 60 q

Two Forms of AMD o Dry Age-Related Macular Degeneration n n o More common Develops slowly Wet Age-Related Macular Degeneration n n More severe Develops quickly

Causes of AMD? o • • Causes are unknown but possible risk factors include: • Smoking Obesity • Poor Diet • Exposure to UV light • • High Cholesterol Hypertension Hereditary Race Gender

Symptoms of AMD q q q Blurriness Wavy Lines Blind Spot http: //www. preservision. com/en/what-is-amd/visionsimulator/

Dry AMD o o o Usually affects both eyes Light Sensitive cells in the macula begin to breakdown and die Presents of Drusen n yellow spots under the retina Photograph of a healthy eye Photograph of an eye with dry AMD

Wet AMD o o o Abnormal blood vessel growth Blood and fluid leak under the macula Leads to scarring Photograph of a healthy eye Photograph of an eye with wet AMD

Treatments Dry AMD Wet AMD o No cure or treatments o o Vitamins o n Some studies show specific combinations of vitamins can slow the progression and impact No cure Treatments n n n Injections into the eye Photodynamic Therapy Laser Therapy

Tools to Detect Progression of AMD o o The Amsler Grid is a simple test to detect early signs of AMD Demonstration of Reduced Visual Acuity http: //www. lucentis. com/get-support

Case Study: Ernest Smith o o o o Age-Related Macular Degeneration Advanced Wet AMD in OS Caused by oxidative stress Used optical coherence tomography test Treatment available: Thermal Laser Therapy Daily monitor: Amsler Grid Had to have treatment again

References About wet AMD. (n. d. ). What is Wet AMD. Retrieved July 15, 2014, from http: //www. lucentis. com/information/wet-age-related-macular-degeneration Boyd, K. (2013, September 1). What Is Age-Related Macular Degeneration? . - Eye M. D. -approved information from Eye. Smart. Retrieved July 15, 2014, from http: //www. geteyesmart. org/eyesmart/diseases/age-related-macular-degeneration/index. cfm Wet macular degeneration. (n. d. ). Definition. Retrieved July 15, 2014, from http: //www. mayoclinic. org/diseases-conditions/wet-macular-degeneration/basics/definition/con 20043518 What is Age-Related Macular Degeneration (AMD)? . (n. d. ). Bausch + Lomb. Retrieved July 15, 2014, from http: //www. preservision. com/en/what-is-amd/ WHAT IS AMD? . (n. d. ). What is Age-Related Macular Degeneration? . Retrieved July 15, 2014, from http: //www. amdawareness. org/asrs/what-is-amd