Investigating the key membrane protein changes during in
Investigating the key membrane protein changes during in vitro erythropoiesis of protein 4. 2 (−) cells (mutations Chartres 1 and 2) by Emile van den Akker, Timothy J. Satchwell, Stephanie Pellegrin, Joanna F. Flatt, Michel Maigre, Geoff Daniels, Jean Delaunay, Lesley J. Bruce, and Ashley M. Toye haematol Volume 95(8): 1278 -1286 July 31, 2010 © 2010 by Ferrata Storti Foundation
Erythrocyte membrane analysis reveals protein 4. 2 deficiency. Emile van den Akker et al. Haematologica 2010; 95: 12781286 © 2010 by Ferrata Storti Foundation
The band 3 -ankyrin-1 association is attenuated in protein 4. 2(−) erythrocytes. Emile van den Akker et al. Haematologica 2010; 95: 12781286 © 2010 by Ferrata Storti Foundation
Protein 4. 2 deficiency affects the extractability of band 3 macrocomplex proteins. Emile van den Akker et al. Haematologica 2010; 95: 12781286 © 2010 by Ferrata Storti Foundation
There are no gross defects in protein 4. 2(−) in vitro erythropoiesis with respect to expansion, proliferation, cell volume, hemoglobinization, enucleation and cell morphology. Emile van den Akker et al. Haematologica 2010; 95: 12781286 © 2010 by Ferrata Storti Foundation
Immunoblotting of proteins from control and 4. 2(−) erythroblast differentiation courses reveal several hallmarks of protein 4. 2 deficiency as observed in erythrocytes. Emile van den Akker et al. Haematologica 2010; 95: 12781286 © 2010 by Ferrata Storti Foundation
The relationship between CD 47 and CD 44 is not reciprocal. Emile van den Akker et al. Haematologica 2010; 95: 12781286 © 2010 by Ferrata Storti Foundation
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