Introduction to Teratogenicity Diagnostic Techniques Aims of Diagnostic

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. Introduction to Teratogenicity. Diagnostic Techniques. Aims of Diagnostic Techniques. Islamic Law and TOP.

. Introduction to Teratogenicity. Diagnostic Techniques. Aims of Diagnostic Techniques. Islamic Law and TOP. Community opinion . Conclusion and Recommendation

. 15% of newborns have a single minor malformation. Major congenital malformation constitute 10%

. 15% of newborns have a single minor malformation. Major congenital malformation constitute 10% of abortion , 3% of all deliveries , about 30% of all stillbirths, neonatal deaths and infant deaths. Perinatal mortality due to malformation is around 2. 5/ 1000. CNS malformation contributes to 10/ 1000 of P. M

. Direct visualisation of the defect e. g Anencephaly. Detection of markers of chromosomal

. Direct visualisation of the defect e. g Anencephaly. Detection of markers of chromosomal defects. Direction of instrument during invasive procedure. Doppler ultrasound

. Termination of abnormal fetus ? ? ? . Reassurance of family. Stressing of

. Termination of abnormal fetus ? ? ? . Reassurance of family. Stressing of family. Fetal therapy

. Early diagnosis of fetal anomalies , so TOP becomes possible a) Preimplant. b)

. Early diagnosis of fetal anomalies , so TOP becomes possible a) Preimplant. b) U/s c) CVS d) early amniocen. . Establishment of genetic labs. Encourage training in fetal therapy

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