Introduction to Oral Cancer Gene Database B 92902025

Introduction to Oral Cancer Gene Database ．資訊三 朱民晃 B 92902025 ．資訊三 陳皓遠 B 92902062

The Tumor Gene Family Databases

Introduction(1/2) • http: //www. tumor-gene. org/ • The Tumor Gene Family of Databases contains information about genes which are targets for cancer-causing mutations; proto-oncogenes and tumor supressor genes. • These databases are designed to for biomedical researchers who work with tumor genes.

Introduction(2/2) • Tumor Gene Database • Breast Cancer Gene Database • Oral Cancer Gene Database

Oral Cancer Gene Database • What information dose the database contain? • This database contains information about genes which are targets for cancer-causing mutations in oral cancers. • List of Oral Cancer Genes • A member of the Tumor Gene Database family • http: //www. tumor-gene. org/Oral/oral. html

Get the list of Oral Cancer Genes (1/2) Click here to get information of the Oral cancer list

Get the list of Oral Cancer Genes (2/2) • List of Oral Cancer Genes

How to search the database (1/4) Key in a Gene Name or a word in a fact you want to search

How to search the database (2/4) Click the “Search” button to search

How to search the database (3/4) Get 1 match of the gene “BAX” Click the hyperlink of “BAX”

How to search the database (4/4) OMIM ID Number of NCBI OMIM ID Number

What can we get ? (1/2) • Cell Type Distribution • Clinical • Complementation • Function • Gene Frequency (Tumors) • Protein Binding • Regulation

What can we get ? (2/2) Link to Citation of NCBI Flag

Flags Primary Fact from a Full Paper Primary Fact from an Abstract Secondary Fact from a Full Paper Secondary Fact from an Abstract Primary Fact from a Review Secondary Fact from a Review Unknown

Link to Gene. Cards (1/2) Click here to link to Gene. Cards website

Link to Gene. Cards (2/2)

NCBI – OMIM (1/4) Remember to choose “OMIM” *600040 , the OMIM ID Number

NCBI – OMIM (2/4) Click here; go to the OMIM homepage. Click “FAQ” to get details about OMIM

NCBI – OMIM (3/4) What do the symbols preceding a MIM number represent?

NCBI – OMIM (4/4) Ex: An asterisk (*) before an entry number indicates a gene of known sequence.

Conclusion • We can search the information about oral gene in the database. • We can get the OMIM ID about the gene in the NCBI database. • We can get the list of genes in the oral database. • We can link to Gene. Cards website.

Thanks for your attention.