Introduction to Enzymes Proteins Chains of amino acids

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Introduction to Enzymes

Introduction to Enzymes

Proteins • Chains of amino acids • Enzymes are proteins • Enzymes serve as

Proteins • Chains of amino acids • Enzymes are proteins • Enzymes serve as catalysts that can spead up or slow down reactions • Enzymes ALWAYS remain unchanged in the reaction AA AA AA

Definitions • Substrate- monomers that bind to the active site of an enzyme •

Definitions • Substrate- monomers that bind to the active site of an enzyme • Active site- area on enzyme where substrate binds • Product- what the enzyme produces

Each enzyme acts on a specific substrate. Two substrates Enzyme Active site of the

Each enzyme acts on a specific substrate. Two substrates Enzyme Active site of the enzyme

induced-fit theory states that the binding of a substrate or some other molecule to

induced-fit theory states that the binding of a substrate or some other molecule to an enzyme causes a change in the shape of the enzyme so as to enhance or inhibit its activity. Enzyme The active site is like a lock The substrates fit like a key in a lock

Lock and Key Model The activation energy for these substrates to bind together has

Lock and Key Model The activation energy for these substrates to bind together has been lowered by the enzyme. Chemical reaction!!! Enzyme

Basic Enzyme Diagram The substrates have reacted and changed into the product Enzyme is

Basic Enzyme Diagram The substrates have reacted and changed into the product Enzyme is unchanged Active site

Lactose, a milk sugar is broken down into glucose and galactos with the enzyme

Lactose, a milk sugar is broken down into glucose and galactos with the enzyme lactase.

In Biology when a word ends in –ase it is more than likely it’s

In Biology when a word ends in –ase it is more than likely it’s an enzyme. Guess what polymers are broken down by these enzymes and what monomers are created? Polymer Monomer • Protease ___________ • Sucrase ___________ • Lipase ___________