Introducing the new H 4 i Launch Training

Introducing the new H 4 i Launch Training 1 H 4 i Launch Training © Res. Med 2008 June Global leaders in sleep and respiratory medicine

Agenda • Overview • H 3 i/H 4 i Visual Differences • H 4 i Humidity Performance • Competitor Comparison • H 4 i Water Chamber Variants • New H 4 i Cleaning Plug • H 4 i Promotional Material • FAQs 2 H 4 i Launch Training © Res. Med 2008 June

Overview What’s new? • Specifically designed to support the high flow rates and pressures typical in bilevel therapy • Unparalleled performance compared to other integrated humidifiers • 30% more humidity than H 3 i • Two new water chambers: – Cleanable water chamber with removable tub plate – Low cost water chamber • Supports entire range of S 8, S 8 II and VPAP IV 3 H 4 i Launch Training © Res. Med 2008 June

H 3 i/H 4 i Visual Differences H 3 i H 4 i Round front allows greater water capacity Removed H 4 i name for clean branding focus on Res. Med and the flow generators Thumb locator for easier closing 4 H 4 i Launch Training © Res. Med 2008 June H 3 i H 4 i Larger heater plate for better heat transfer

H 4 i Humidifier Performance 30% Performance improvement Note: This represents the amount of humidity the devices can add to the air at the given flow rate. *Tested to ISO 8185, at 10 cm H 2 O bias flow and maximum device output 5 H 4 i Launch Training © Res. Med 2008 June

Competitor Comparisons Res. Med H 4 i “Best in class” Note: This represents the amount of humidity the devices can add to the air at the given flow rate. * All devices tested to ISO 8185, at 50 l/min and maximum device output 6 H 4 i Launch Training © Res. Med 2008 June

H 4 i Water Chamber Variants Inverted water chamber shows removable base for easy cleaning access H 4 i Water Chamber (sealed) • • • Low cost 6 -month life Opaque appearance Standard water chamber for Americas Available as accessory for ROW H 4 i Cleanable Water Chamber • • Removable base plate for easy cleaning 2 -year life Similar transparent appearance as the H 3 i Cleanable does not equal MPMU Note: The sealed H 4 i water chamber will be available from November 1, 2008. A fixed plate version of the cleanable water chamber is being used in the interim. 7 H 4 i Launch Training © Res. Med 2008 June

New H 4 i Cleaning Plug Added functionality The cleaning plug can now be used to measure the one part vinegar when conducting the weekly cleaning. • Fill the cleaning plug to the rim with vinegar and pour into empty water chamber. New shape to fit H 4 i water chambers • Add clean water to the water chamber until the solution reaches the maximum water level mark. • Done. No more messing around with measuring jugs. 8 H 4 i Launch Training © Res. Med 2008 June

H 4 i Promotional Material H 4 i Component Card 9 H 4 i Launch Training © Res. Med 2008 June H 4 i Fact Sheet

FAQs Q. Does the Res. Med tubing wrap provide any benefits in humidification and comfort? A. Yes, the tubing wrap helps retain the heat as the air travels down the tube, providing warmer air to the mask. This warmth provides greater comfort and increases the amount of humidity able to be provided. This graphs shows how the saturation point increases with the temperature of the air. 13% more AH 10 H 4 i Launch Training © Res. Med 2008 June An increase as little as 2°C in air temperature results in a 13% increase in the amount of humidity able to be delivered to the mask. This can make all the difference between rainout and comfortable therapy.

FAQs Q. Can the H 4 i water chambers be used with the Humid. Aire 3 i docking station? A. Yes, by replacing the H 3 i top cover and seal with the H 4 i variants, you can use either H 4 i water chamber on a H 3 i docking station. (sealed) Note: You cannot use the H 3 i water chamber on the H 4 i docking station. 11 H 4 i Launch Training © Res. Med 2008 June

FAQs Q. Why do the H 4 i water chambers hold less water than the H 3 i water chamber? A. The H 3 i has 60 m. L of unusable water. While the stated capacity is 415 m. L, only 355 ml can be used. When the water level falls below the level of the tub plate, the remaining water is not usable. The H 4 i is designed with a large plate as the base, therefore all 390 m. L of water can be used. Total Volume Usable Volume H 3 i 415 ml 355 ml H 4 i 390 ml 12 H 4 i Launch Training © Res. Med 2008 June

FAQs Q. Why is the H 4 i still being shipped with the carry pouch? How does the pouch fit into the new black flow generator bag? A. The new black bag is designed to be used without the carry pouch (see picture). The carry pouch does not fit into the new black bag. The H 4 i is initially being shipped with the carry pouch, as unfortunately there are still products being sold with the original blue bag. This bag requires the carry pouch to ensure adequate protection for the humidifier. The carry pouch is expected to be removed from the H 4 i packaging towards the end of the year. 13 H 4 i Launch Training © Res. Med 2008 June

FAQs Q. How do the H 3 i and H 4 i control dial settings differ? A. The graph below indicates the corresponding H 4 i control dial setting for each H 3 i setting. H 3 i Humidity Dial Settings 1 2 3 4 5 6 Improved Humidity Performance 1 2 3 4 5 6 H 4 i Humidity Dial Settings Above setting 3. 5, the H 4 i—with 30% more output—exceeds the maximum H 3 i output. 14 H 4 i Launch Training © Res. Med 2008 June