Integumentary System The skin the largest organ in

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Integumentary System • The skin - the largest organ in the body by weight

Integumentary System • The skin - the largest organ in the body by weight • Various accessory structures – hair, nails, and glands

Functions of the Skin Protection Excretion Regulation of body temperature Sensory receptors Vitamin D

Functions of the Skin Protection Excretion Regulation of body temperature Sensory receptors Vitamin D synthesis Blood reservoir Immunity

Functions of the Skin Protection From water loss From injury From chemicals and microorganisms

Functions of the Skin Protection From water loss From injury From chemicals and microorganisms Excretion Urea Uric acid

Functions of the Skin Sensory Receptors Light touch detection – Meissner’s Corpuscle Pressure detection

Functions of the Skin Sensory Receptors Light touch detection – Meissner’s Corpuscle Pressure detection – Pacinian Corpuscle Vitamin D synthesis Ultraviolet rays from sunlight activate it Used for bone strength and homeostasis

Functions of the Skin Blood Reservoir Contains 10% of the body’s blood vessels Immunity

Functions of the Skin Blood Reservoir Contains 10% of the body’s blood vessels Immunity Contains Langherhan cells Interact with T-helper cells in immune responses

General Structure & Function Skin (cutaneous membrane) Epidermis Outermost layer-protection Dermis Inner layer-nourishment of

General Structure & Function Skin (cutaneous membrane) Epidermis Outermost layer-protection Dermis Inner layer-nourishment of epidermis Stratified squamous Connective tissue Smooth muscle tissue Nervous tissue Blood Hypodermis (subcutaneous Distinct layer beneath the skin -insulation membrane) Adipose tissue

General Structure Skin (cutaneous membrane)

General Structure Skin (cutaneous membrane)

Epidermis (5 layers) Stratum corneum Outermost Dead keratinized epithelial cells Stratum lucidum Translucent Only

Epidermis (5 layers) Stratum corneum Outermost Dead keratinized epithelial cells Stratum lucidum Translucent Only in thick skin (soles/palms) Stratum granulosum 3 -5 layers of flattened granular cells filled w/ keratin Stratum spinosum Many layers of rounded cells w/ large nuclei Stratum basale Deepest Single row of cuboidal mitosing cells Melanocytes (produce melanin

Dermis (2 layers) General-contains blood vessels, nerves, hair follicles, glands Papillary 20% Loose areolar

Dermis (2 layers) General-contains blood vessels, nerves, hair follicles, glands Papillary 20% Loose areolar connective tissue Dermal papillae Meissner’s Corpuscles –light touch Reticular 80% Dense irregular connective tissue Collagen, elastic, and reticular fibers Pacinian Corpuscles-heavy pressure

Hair Follicles Structures Hair follicle Hair root Hair papilla Hair shaft Arrector pilli Sebaceous

Hair Follicles Structures Hair follicle Hair root Hair papilla Hair shaft Arrector pilli Sebaceous glands Functions

Nails Structures Nail plate Nail bed Lunula Functions protection

Nails Structures Nail plate Nail bed Lunula Functions protection

Skin Glands Sebaceous Hair Eccrine Odorless sweat abundant Apocrine Less numerous Develop odor

Skin Glands Sebaceous Hair Eccrine Odorless sweat abundant Apocrine Less numerous Develop odor