Informatics Research Directions Sys MOEra Sys BIO Workflows
Informatics Research Directions
Sys. MO/Era. Sys. BIO • Workflows running behind a web page – Better support for viewing data inputs/outputs/tweaking parameters • Research Objects (with and without workflow components) • Read/write from spreadsheets and in Sys Bio formats
Systems Biology • Workflows for finding and extracting parameter values and/or experimental data for plotting against model simulations • Pathway analyses • Omics analyses – microarray, proteomics etc • Comparative genomics
Main Areas • Next Gen sequencing – Downstream analysis – Genomic data mining • Medical Systems Biology – Very familiar comparative genomics, multi-omics analysis and eventually linking data and models – Big distributed consortia, impact • Bio. Banking
Other local users • Ancient DNA Next Gen data. Ancient TB infection • Sort of local – Afsaneh pulmonary diseases systems biology • Work with gynacolgy department – rerunn of Paul and Afsaneh’s microarray workflows
Features from other projects that would be useful • Sparql service from e. Lico • Shim library from Next Gen workbench • Better support for adding local/remote perl scripts – external tools? /scape • More support for running workflows over web • Renderers – – cytoscape (elico), – DAS/genome browser (TSB? )
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