Inflammation 1 What are the four classic signs Slides: 23 Download presentation Inflammation 1. What are the four classic signs of INFLAMMATION (affected tissue’s response to trauma) Redness, Swelling, Heat, and Pain. 2. What (usually) initiates the process? ? Remember the INTEGUMENTARY SYSTEM (skin) that usually protects you? 3. What is that layer of the upper epidermis that protects our body? ? 5. What happens when this layer is breached? Bacteria that are normally harmless become infectious 6. Here’s a mast cell. What’s it do? ? Mast cell have various capabilities. Which one is used in inflammation? 7. For vasodilatation to occur, what cells go into action? What does this image show? 8. What’s going on here? DIAPEDESIS: the passage of blood cells through the walls of the capillaries, typically accompanying inflammation. What cells perform diapedesis? ? Behold the Neutrophil YOU SHALL RECOGNIZE ME BECAUSE MY NUCLEUS HAS A MULTILOBULATE D SHAPE Let’s watch an animation: https: //www. youtube. com/watch? v=R 8 Vzqu. Hdw. Zw “I Love to Kill” the Neutrophil Which killing strategy should we focus on? 9. CHEMOTAXIS: the movement of an organism or cell in response to a chemical stimulus. ? Let’s watch another video: https: //www. youtube. com/watch? v=ZUUfd. P 87 Ssg 10. Enter the MACROPHAGE The macrophage also cleans up dead neutrophils 11. Finally, the fibroblast secretes fibers to repair damaged tissue. ? ? Quick Review: What were those four signs again? ? ?