Implementation of erythroid lineage analysis by flow cytometry

Implementation of erythroid lineage analysis by flow cytometry in diagnostic models for myelodysplastic syndromes by Eline M. P. Cremers, Theresia M. Westers, Canan Alhan, Claudia Cali, Heleen A. Visser-Wisselaar, Dana A. Chitu, Vincent H. J. van der Velden, Jeroen G. te Marvelde, Saskia K. Klein, Petra Muus, Edo Vellenga, Georgina E. de Greef, Marie. Cecile C. J. C. Legdeur, Pierre W. Wijermans, Marian J. P. L. Stevens-Kroef, Pedro da Silva-Coelho, Joop H. Jansen, Gert J. Ossenkoppele, and Arjan A. van de Loosdrecht haematol Volume 102(2): 320 -326 January 31, 2017 © 2017 by Ferrata Storti Foundation

Erythroid markers that comprise the IMDS-Flow erythroid FC score and the cumulative score, stratified by patient group. Eline M. P. Cremers et al. Haematologica 2017; 102: 320 -326 © 2017 by Ferrata Storti Foundation

The parameters that describe the original integrated MDS-FC score, the erythroid score and the diagnostic score. Eline M. P. Cremers et al. Haematologica 2017; 102: 320 -326 © 2017 by Ferrata Storti Foundation

The addition of the erythroid evaluation to the diagnostic score. 13, 14. Eline M. P. Cremers et al. Haematologica 2017; 102: 320 -326 © 2017 by Ferrata Storti Foundation

The addition of the erythroid evaluation to the integrated MDS-FC score (i. FS). 16. Eline M. P. Cremers et al. Haematologica 2017; 102: 320 -326 © 2017 by Ferrata Storti Foundation

Comparison of dyserythropoiesis as assessed by cytomorphology and flow cytometry. Eline M. P. Cremers et al. Haematologica 2017; 102: 320 -326 © 2017 by Ferrata Storti Foundation

MDS-FC results in the MDS and control group. Eline M. P. Cremers et al. Haematologica 2017; 102: 320 -326 © 2017 by Ferrata Storti Foundation

WHO-classifications within different MDS-FC groups. Eline M. P. Cremers et al. Haematologica 2017; 102: 320 -326 © 2017 by Ferrata Storti Foundation