Immune System Lines of Defense First Line of

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Immune System Lines of Defense

Immune System Lines of Defense

First Line of Defense: Physical Barriers

First Line of Defense: Physical Barriers

Physical Barriers: u Skin u Body Secretions -mucous membrane -sweat -tears saliva Cilia on

Physical Barriers: u Skin u Body Secretions -mucous membrane -sweat -tears saliva Cilia on cells which secrete mucous in the respiratory tract (Modern Bio. 956)

Second Line of Defense: Inflammatory Response

Second Line of Defense: Inflammatory Response

Inflammatory Response: u Body’s initial local healing reaction to an injury u Phagocytes: white

Inflammatory Response: u Body’s initial local healing reaction to an injury u Phagocytes: white blood cells that surround, engulf, and consume foreign particles u Macrophage: largest phagocytes that consume large numbers of invading pathogens

Macrophage engulfing yeast cells

Macrophage engulfing yeast cells

Macrophage attacking ecoli

Macrophage attacking ecoli

Inflammatory Response 1. 2. 3. 4. 5. Small cut triggers Injured cells release a

Inflammatory Response 1. 2. 3. 4. 5. Small cut triggers Injured cells release a chemical alarm Capillaries swell Phagocytes released Phagocytes destroy pathogens

Inflamatory Response

Inflamatory Response

Third Line of Defense: The Immune System

Third Line of Defense: The Immune System

The Immune System 1. u. Immunity: the body’s ability to recognize and resist infection

The Immune System 1. u. Immunity: the body’s ability to recognize and resist infection by specific pathogens/toxins

2. u. Active immunity: your body produces its’ own substances (antibodies) to fight pathogens

2. u. Active immunity: your body produces its’ own substances (antibodies) to fight pathogens http: //www. merck. com/media/mmhe 2/figures/fg 183_3. gif

3. u Passive immunity: antibodies are produced by another source u Vaccine: formed from

3. u Passive immunity: antibodies are produced by another source u Vaccine: formed from weakened, dead, or parts of pathogens to develop immunity http: //www. vpul. upenn. edu/ohe/library/cold/vaccine. jpg