How do cells multiply CellDevelopmental Biology Group The

How do cells multiply? Cell/Developmental Biology Group The Cyclers r te r Pe vna Katie Nemeth Sta nle Lo y V Do et zie r Greg Beitel Ca tte e d u Cla avis D Steve Chordas, III

Background of the Class (for SI participants only) • Course: Introduction to Biology (Majors) • Class Size: 55+ students • Module: Cell Biology, two-week (6 lectures) teachable unit on cell cycle • First class of the unit • What do students know already? Nucleotides, DNA, chromosomes, and organelles • Students will learn about the cell cycle.

The Cell Cycle Who cares?

How does cell division relate to human health? Down Syndrome: 1 in 800 babies born in US Cancer: 23% of all deaths in US in 2007 resulted from cancer

What will we learn today? • We will be able to explain why each of the phases of the cell cycle occur in the order that they do

How will we learn how cells divide? Overview: In small groups (two groups per table) we will: • Brainstorm to determine what the most basic events the cell must undergo to achieve division • Generate a common list of events • Determine the order in which the events occur

Brainstorm Question… Come up with a list of actions or events that an animal cell must undergo to achieve division. 2 minutes

Work in your groups to arrange the notes in the order that would make the cell divide… (3 min)

cell cycle

Where do we go from here? Today • We will be able to sequence the events of the cell cycle and explain why each of the phases occur in the order that they do Rest of Teachable Unit • To know what checkpoints and their functions are • To understand the functions of cyclins and CDKs (e. g. concentrations at different stages of cell cycle, different specificities, activities regulated by other relate to diseases proteins) • Mitosis: what is it and what is the outcome? • What actions occur to move the chromosomes and divide the two cells? • To understand diseases related to the cell cycle