Hormones of the Pituitary Gland 24022021 Dr Omary

Hypothalamus Neuronal cells Epitheloid cells Neuro hypophysis Posterior Pituitary Adeno hypophysis Anterior Pituitary Pars

The Anterior Pituitary cells and Hormones Acidophils 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

The Posterior Pituitary cells and Hormones Paraventricular neurones Supraoptic neurones Magnocellular Neurone Posterior Pituitary

Hypothalamus controls pituitary secretions Releasing or Inhibiting Hormones Nerve Signals 24/02/2021 Dr. Omary Chillo

Hypothalamic-Hypophysial Portal System 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

Hypothalamus Releasing/Inhibitory Hormones Thyrotropin-releasing H (TRH) TSH Corticotropin-releasing H (CRH) GH-releasing H (GHRH) GH

Which kind of hormones from the anterior pituitary will be released following a removal

Anterior Pituitary Hormones TSH CRH Anterior Pituitary FSH, LH Prolac tin Gro wth 24/02/2021

The Growth Hormone increase in cell size (hypertrophy) increase in number of cells (hyperplasia)

Protein Deposition in Tissues 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

Regulation of GH release GHRH somatostatin Gi (-) Gs c. AMP PKA PIT-1 GH

Abnormalities of Growth Hormone • Due to lack of GH release from the pituitary,

Thanks 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

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Hormones of the Pituitary Gland 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

24/02/2021 Dr. Omary Chillo (MD, Ph. D)

Hypothalamus Neuronal cells Epitheloid cells Neuro hypophysis Posterior Pituitary Adeno hypophysis Anterior Pituitary Pars intermedia 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

The Anterior Pituitary cells and Hormones Acidophils 24/02/2021 Dr. Omary Chillo (MD, Ph. D) Somatotropes GH Corticotropes ACTH Thyrotropes TSH Gonadotropes FSH lactotropes PRL LH

The Posterior Pituitary cells and Hormones Paraventricular neurones Supraoptic neurones Magnocellular Neurone Posterior Pituitary Oxytocin 24/02/2021 Dr. Omary Chillo (MD, Ph. D) ADH

Hypothalamus controls pituitary secretions Releasing or Inhibiting Hormones Nerve Signals 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

Hypothalamic-Hypophysial Portal System 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

Hypothalamus Releasing/Inhibitory Hormones Thyrotropin-releasing H (TRH) TSH Corticotropin-releasing H (CRH) GH-releasing H (GHRH) GH GH-inhibiting H (Somatostatin) GH Gonadotropin-releasing H (Gn. RH) Prolactin-inhibitory H (PIH) 24/02/2021 ACTH Dr. Omary Chillo (MD, Ph. D) FSH PRL Clip LH

Which kind of hormones from the anterior pituitary will be released following a removal of hypothalamus? 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

Anterior Pituitary Hormones TSH CRH Anterior Pituitary FSH, LH Prolac tin Gro wth 24/02/2021 Hor mo ne Dr. Omary Chillo (MD, Ph. D)

The Growth Hormone increase in cell size (hypertrophy) increase in number of cells (hyperplasia) Actions of Growth Hormone: - increases skeletal growth - increases muscular growth - increases amino acid uptake and protein synthesis - increased use of lipids for energy - decreased glucose uptake in tissues (diabetogenic) 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

Protein Deposition in Tissues 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

24/02/2021 Dr. Omary Chillo (MD, Ph. D)

Regulation of GH release GHRH somatostatin Gi (-) Gs c. AMP PKA PIT-1 GH synthesis • GH levels are low during the day, but increase during sleep. • There is an overall increase in GH levels during puberty. 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

Abnormalities of Growth Hormone • Due to lack of GH release from the pituitary, or lack of GH receptor expression____ • Excessive secretion of growth hormone____ and ____ ? Growth Hormone effect on Aging 24/02/2021 Dr. Omary Chillo (MD, Ph. D)

The Posterior Pituitary cells and Hormones Paraventricular neurones Supraoptic neurones Magnocellular Neurone Posterior Pituitary Oxytocin 24/02/2021 Dr. Omary Chillo (MD, Ph. D) ADH

Thanks 24/02/2021 Dr. Omary Chillo (MD, Ph. D)