Homework 1 is posted and due 917 Bonus

• Homework #1 is posted and due 9/17 • Bonus #1 is posted and due 10/24 • Discussions start M 9/10

• Two representations of the DNA double helix Figure 7 -9 Fig 7. 9

The relationship between DNA and genes a gene - DNA used to produce RNA or protein promoter coding region terminator non-gene DNA

Five Perspectives of a Gene

Genes act as units of heredity…storing and passing on information.

Genes are seen as a cause of disease

Sickle-cell anemia is caused by a single nucleotide change in the hemoglobin gene Fig 6. 5

Fig 8. 11 Genes code for proteins

Genes code for proteins… Proteins are the “doers” of the cell. They act as: • Enzymes • Structural Support • Transporters • Signals

Genes act as switches, controlling development

Genes are replicators (selfish gene) From “Biology 7 th ed. ” by Campbell et al fig 19. 14

Fig 5. 25 Viruses infect living cells, take over, and produce more virus.

Bodies are vessels for the transmission of genes

Five Perspectives of Genes: 1. Genes act as units of heredity 2. Genes are seen as a cause of disease 3. Genes code for proteins 4. Genes act as switches, controlling development 5. Genes are replicators (selfish gene)

Transposons

Genes are replicators (selfish gene) Transposons: mobile DNA

Barbara Mc. Clintock, discoverer of transposons

Transposons are self-moving DNA Fig 14. 8

Fig 14. 8 Transposons move within genomes via the action of transposase

Fig 14. 4 transposase transposon

Fig 14. 4

Genes are replicators (selfish gene) From “Biology 7 th ed. ” by Campbell et al fig 19. 14

Genes are replicators (selfish gene) Transposons: mobile DNA

Five Perceptions of Genes: 1. Genes act as units of heredity 2. Genes are seen as a cause of disease 3. Genes code for proteins 4. Genes act as switches, controlling development 5. Genes are replicators (selfish gene)