HIVAIDS What does HIVAIDS stand for n HIV

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HIV/AIDS

HIV/AIDS

What does HIV/AIDS stand for? n HIV (Human Immunodeficiency Virus) n AIDS (Acquired Immunodeficiency

What does HIV/AIDS stand for? n HIV (Human Immunodeficiency Virus) n AIDS (Acquired Immunodeficiency Syndrome)

What causes HIV/AIDS? n The human immunodeficiency virus causes HIV infection and AIDS. People

What causes HIV/AIDS? n The human immunodeficiency virus causes HIV infection and AIDS. People who are infected with this virus may not have any symptoms and may not realize they have become infected.

Definition of HIV n HIV is a retrovirus that infects and kills the CD

Definition of HIV n HIV is a retrovirus that infects and kills the CD 4+ T cells of the human immune system. As CD 4+ T cells are destroyed, the immune system fails, leading to AIDS. n CD 4+ cells are a type of white blood cell that help our bodies fight infection

Definition of AIDS n People with HIV with a CD 4+ T cell count

Definition of AIDS n People with HIV with a CD 4+ T cell count below 200 m. L of blood or 14% of all lymphocytes.

HIV Statistics n n n n n CDC estimates between 800, 000 and 900,

HIV Statistics n n n n n CDC estimates between 800, 000 and 900, 000 U. S. residents are living with HIV. Of those people, approximately one-third of them are unaware of their infection. 40, 000 new HIV infections occur every day worldwide, with half occurring in people under the age of 25. AIDS is the 6 th leading cause of death among 15 -24 year olds and their infection is usually the result of sexual behavior. Two teenagers an hour become infected with HIV in the United States. New York State has the greatest number of AIDS cases with 194, 341 Even without NYC, New York ranks in the top 7 states. There are 23 AIDS cases in Cortland County. Only 10% of people infected with HIV tell their partners about it.

How is HIV/AIDS Contracted? n Vaginal and anal secretions n Semen n Blood (IV

How is HIV/AIDS Contracted? n Vaginal and anal secretions n Semen n Blood (IV drug use/blood transfusion) ¨ Do we need to worry about blood transfusions today? n Mother to child (breast milk/labor)

You Can Not Get HIV From… n n n n Closed-mouth kissing Hugging Touching,

You Can Not Get HIV From… n n n n Closed-mouth kissing Hugging Touching, holding, or shaking hands Coughing or sneezing Sharing food or eating utensils Sharing towels or combs Sharing bathroom facilities or water fountains

How HIV progresses into AIDS: WINDOW PERIOD ASYMPTOMATIC AIDS

How HIV progresses into AIDS: WINDOW PERIOD ASYMPTOMATIC AIDS

STAGE 1: WINDOW PERIOD Point of infection n Takes 1 -3 months for antibodies

STAGE 1: WINDOW PERIOD Point of infection n Takes 1 -3 months for antibodies to show up on an HIV test n A person in the window period would test negative even though are actually positive n Can infect another person n Person looks and feels fine n T-cells are approximately 1000 per milliliter of blood n

Stage 2: ASYMPTOMATIC Stage lasts three months after infection to approximately 10 years after

Stage 2: ASYMPTOMATIC Stage lasts three months after infection to approximately 10 years after infection n Immune system is under attack n T-cells are being destroyed n Person still looks and feels fine n Experiencing no symptoms of sickness n Can infect another person n T-cells are approximately 1000 -500 per milliliter of blood n

Stage 3: SYMPTOMATIC Typically three years to ten years after infection, a person will

Stage 3: SYMPTOMATIC Typically three years to ten years after infection, a person will develop symptoms of HIV n Immune system is still being destroyed n Person begins to feel sick: weight loss, fatigue, diarrhea, night sweats, vomiting n Can still infect another person n Person’s t-cell count drops to approximately 500 -200 per milliliter of blood n

People who have HIV symptoms experience one or more of the following: ¨ flu-like

People who have HIV symptoms experience one or more of the following: ¨ flu-like symptoms ¨ swollen glands ¨ diarrhea ¨ night sweats ¨ weight loss, fatigue ¨ yeast infections ¨ pneumonia ¨ cancer

Stage 4: AIDS When T-cell count drops below 200 per milliliter of blood, a

Stage 4: AIDS When T-cell count drops below 200 per milliliter of blood, a person is diagnosed with AIDS n A person typically becomes infected with opportunistic diseases like: Karposi’s sarcoma (cancer of blood vessels) or pneumosystic pneumonia, AIDS dementia n A person dies from the opportunistic disease, not from AIDS n

What is an opportunistic infection? n n HIV does not cause death directly. Instead,

What is an opportunistic infection? n n HIV does not cause death directly. Instead, it weakens the body's ability to fight disease. Infections which are rarely seen in those with normal immune systems are deadly to those with HIV. People with HIV can get many infections (called opportunistic infections). Many of these illnesses are very serious, and they need to be treated. Some can be prevented n Examples of opportunistic infections: Pneumonia, Influenza

HIV Testing Who should get tested? n Anyone who has: had unprotected sex shared

HIV Testing Who should get tested? n Anyone who has: had unprotected sex shared needles had a blood transfusion before 1985 had sex or shared needles with someone engaging in the above behaviors n When should you get tested? n 1 -3 months after a risky behavior n

Types of HIV tests Traditional blood test -Confidential- results are kept in a confidential

Types of HIV tests Traditional blood test -Confidential- results are kept in a confidential file; no one but your doctor should see this file unless you give consent. -Anonymous- your name does not go on the file, a number is recorded instead. n Ora-sure rapid HIV test n Ora-quick rapid HIV test n

Treatment There are 30 antiretroviral drugs approved by the Food and Drug Administration to

Treatment There are 30 antiretroviral drugs approved by the Food and Drug Administration to treat people infected with HIV. These drugs fall into four major classes. ¨ Reverse transcriptase (RT) inhibitors interfere with the critical step during the HIV life cycle known as reverse transcription. During this step, RT, an HIV enzyme, converts HIV RNA to HIV DNA. There are two main types of RT inhibitors. n Nucleoside/nucleotide RT inhibitors are faulty DNA building blocks. When these faulty pieces are incorporated into the HIV DNA (during the process when the HIV RNA is converted to HIV DNA), the DNA chain cannot be completed, thereby blocking HIV from replicating in a cell. n Non-nucleoside RT inhibitors bind to RT, interfering with its ability to convert the HIV RNA into HIV DNA.

Treatment Continued… n n Protease inhibitors interfere with the protease enzyme that HIV uses

Treatment Continued… n n Protease inhibitors interfere with the protease enzyme that HIV uses to produce infectious viral particles. Entry and fusion inhibitors interfere with the virus' ability to fuse with the cellular membrane, thereby blocking entry into the host cell. Integrase inhibitors block integrase, the enzyme HIV uses to integrate genetic material of the virus into its target host cell. Multidrug combination products combine drugs from more than one class into a single product.

Protection n Abstinence n Latex condoms

Protection n Abstinence n Latex condoms

How To Reduce Your Risk… EDUCATION n Monogamous relationship n Fewer sex partners n

How To Reduce Your Risk… EDUCATION n Monogamous relationship n Fewer sex partners n Engage in sexual activities at an older age n Avoid drug use n Communication with partner n

Race/ethnicity of persons (including children) with HIV/AIDS diagnosed during 2006 www. cdc. gov Age

Race/ethnicity of persons (including children) with HIV/AIDS diagnosed during 2006 www. cdc. gov Age of persons with HIV/AIDS diagnosed during 2006

Sex of adults and adolescents with HIV/AIDS diagnosed during 2006 www. cdc. gov

Sex of adults and adolescents with HIV/AIDS diagnosed during 2006 www. cdc. gov

Transmission categories of adults and adolescents with HIV/AIDS diagnosed during 2006 www. cdc. gov

Transmission categories of adults and adolescents with HIV/AIDS diagnosed during 2006 www. cdc. gov

Adults and Children Estimated Living with HIV (2007)

Adults and Children Estimated Living with HIV (2007)

AIDS 2007 Statistics Facts and Figures www. kff. org

AIDS 2007 Statistics Facts and Figures www. kff. org

HIV/AIDS Timeline http: //www. kff. org/hivaids/timeline/hivtimeline. cfm

HIV/AIDS Timeline http: //www. kff. org/hivaids/timeline/hivtimeline. cfm

The AIDS Memorial Quilt: Represents lives taken from AIDS

The AIDS Memorial Quilt: Represents lives taken from AIDS

Celebrities that died from AIDS

Celebrities that died from AIDS

Celebrities Living with HIV Magic Johnson

Celebrities Living with HIV Magic Johnson

Where to go for information or testing Jacobus Center n Planned Parenthood n Gynecologist

Where to go for information or testing Jacobus Center n Planned Parenthood n Gynecologist n Urologist n Regular Physician n