HERPES GENITALIS SYPHILIS Mia Smoljan Mentor A mega

HERPES GENITALIS & SYPHILIS Mia Smoljan Mentor: A. Žmegač Horvat

Herpes genitalis l l l STD caused by HSV Remissions and relapses Symptoms: l l l Diagnosis: l l l reddening of the skin with small, fluid-filled blisters and ulcers initial episodes may be more severe – inguinal lymphadenopathy, fever, malaise, headache PCR Tzank test Treatment: Acyclovir

http: //www. youtube. com/watch? v=TY 8 Xh. AKI 7 CI/

l l l Herpes neonatalis Dangerous complication that affects babies born while mother has an active infection during parturition Symptoms appear between 1 st and 2 nd week of life Can affect: l l l l skin CNS eye mouth liver lungs. . . . Prevention: Cesarean section Treatment: Acyclovir

Syphilis l l l Chronic STI caused by Treponema pallidum Acquired via direct sexual contact with the infectious lesions of a person with syphilis PRIMARY SYPHILIS: a few weeks after infection – – chancre/hard ulcer after 4 to 6 weeks heals spontaneously

l SECONDARY SYPHILIS: – – – 1– 6 months (commonly 6 to 8 weeks) after the primary infection symmetrical reddish-pink non-itchy rash on the trunk and extremities condylomata lata (rash becomes flat, broad, whitish lesions) most contagious stage!! meningismus, enlarged lymph nodes, fever. .

l TERTIARY SYPHILIS: – – 1– 10 years after the initial infection formation of gummas = l – – – soft, tumor-like balls of inflammation – granulomas neuropathic joint disease neurosyphilis tabes dorsalis cardiovascular syphilis – ascending aorta!! cor bovinum

l l Diagnosis: serology (VDRL antibody test, TPHA) Treatment: l penicillin