Helsinki Business and Science Park Ltd HBSP provides

Helsinki Business and Science Park Ltd (HBSP) provides development, production and marketing support services for innovations that originate from academic research, but under a business environment. One aim is to create new startup companies through the HBSP incubator system. Existing companies, and research institutes derive a mutual benefit through HBSP. The main fields of operation are biotechnology, diagnostics and medical technologies, food technology and environmental technology. HBSP is located in both the Viikki (Bio) and Meilahti (Medical) campuses in the city of Helsinki, 2008 Jaakko Helenius M. Sc. MBA Managing Director 1

Helsinki Region • Over 1. 2 million inhabitants (population in Finland over 5. 2 million) • Highest level of education in Finland • 16 universities and polytechnics FINLAND Helsinki • More than 60, 000 companies • 30% of jobs of Finland as a whole Finland • Population over 5. 2 million • Enterprises appr. 220 000, 99. 8% SMEs • Mobile phone penetration 91% (2003) • Broadband internet connections penetration 48% (2003) • Finnish R&D to 3. 5% of GDP (2003) 2

Member of Tekel In figures: OPERATIVE COMPANIES • 23 science parks • 550 employees • 100 m€ turnover • 7 500 business contacts SCIENCE PARKS • 1 600 enterprises and other organisations • 32 000 experts • over 1 000 m 2 3

Helsinki Business and Science Park Ltd – HBSP Facts Ownership of HBSP Established 1992 • full-time activity 1996 Facilities (Viikki and Meilahti) • total 16 000 m 2 15 Employees • +4 outsourced Turnover 2. 8 million € 4

Helsinki Region – Strong in industry/academia collaboration Academic quality – University of Helsinki Together with Viikki and Meilahti campuses receive 46 % of the Academy of Finland’s biotech money. • Ranked in 74 th place the Best Universities in the World 11 faculties o 38 000 degree students and 7 500 staff o Annually 4 000 master’s degree and 355 doctorates o Biotech industry in Finland 57 % sector’s jobs established and 67% sector’s turnover comes from Helsinki Region Biotech companies and organizations in Finland totaled 137 • • • Helsinki Region Turku Tampere Kuopio Oulu Others 45 % 32 % 6% 8% 4% 5% (ref. FIB Index 2003) 5

o University Tiede poikkitieteellisyys, neutralius Research Institutes Customers – Tenant Structure Idea Start-ups SME Life Science/High technology Pharmaceutical/Medtech/Welfare/Food/ Other Industries Other service provides law account IT-service market analysis financing etc. . University of Helsinki, University Hospital Helsinki Region 6

• Services – HBSP Premises and Office services – – – • Laboratory and Instrument services – – • [No. ] Year Service facilities Produced services Service providers 1999 7 8 2 2004 23 60 31 Clean-up and waste disposal services (with special demand) Laboratory utensil care Chemical storages, constant temperature rooms Core facility services (University of Helsinki) Business services – – – • Real estate management and maintenance services Office and entrance hall service Security services feasibility, market analysis strategy, business plan business and technology training mentor-program network/co-operation partners Financial services – – alternatives, matching negotiations, agreements • Local and international contact network; Industry, University • Others; Accounting, legal, IT, marketing and library services 7

Viikki – Bio. Campus Institute of Biotechnology One of the largest bio-campuses in Europe University • Four University faculties: Agriculture and Forestry, Biosciences, Pharmacy, Veterinary Medicine Others • Two Centres of Expertise • Game and Fisheries Research • National Veterinary and Food Research Institute of Finland Cultivator II (HBSP) Cultivator I (HBSP) Info Center Korona Facts • 6 000 students • 2 500 staff • 40 (+field 160) hectares 8

Basic and clinical research productively combined University • Faculty of Medicine • Helsinki University Central Hospital Other • Centre of Expertise • National Public Health Institute KTL • Finnish Institute of Occupational Health TTL Facts • 2 000 students • 1 500 staff • 20 hectares FOTO: JUHA TIAINEN Meilahti – Medical Campus University Central Hospital and Hospital District of Helsinki and Uusimaa Biomedicum 9

Companies in Viikki and Meilahti campuses Appr. 55 companies or research groups Nearly 400 employees Cultivator I and II – 30 -40 companies p. a. – 5 research groups from University of Helsinki – 1 research institute Viikki Area – 8 companies Meilahti Area – Biomedicum 2 – 15 companies Kumpula Area – 1 company South Finland – Appr. 250 food(technology) companies 10

Companies by sector and maturity Drug Discovery Diagnostics Glykos Finland ltd. excellence in glycobiology Manufacturing Treatment Food technology Wellness Services Start-up Later Stage 11

Finnish Innovation system – Network, Partners Idea, Innovation Start-ups, Spin-off Start-ups/SME (Growth) Evaluation Strategy, Business Plan Finance Universities Innovation Agents Research Institutes (University) Industry TEKES (R&D) TULI TUPAS (Tekes) Venture Cup Licentia Foundation for Finnish Inventions Mentors HSE Hanken Finpro … Service providers LIKSA Sitra Institutions Private Investors Venture Capital (seed/late) (Tekes, Sitra) Tekes loans, R&D TE-Center TESI Finnvera Banks Industrial Investors Helsinki Business and Science Park Ltd 12

Special themes in the Finnish system Clusters • The Centre of Expertise Programme (OSKE), is a special government programme aimed at focusing regional resources and acticvities on development areas on key national importance • 13 clusters: Health. BIO, Food Tech, ICT, Cleantech, Nanotech, Energy Tech, Forestry, etc. • The local centres of expertize (21) take care of implementing • Some (local) clusters which are initiated by the relevant industry itself and are functioning without major public support • The cluster - idea is well received in Finland is widely implemented 13

Special themes in the Finnish system Tekes – Finnish Funding Agency for Technology and Innovation • Large national, publicly funded and controlled project provider for both research intitutes, large corporations and SME’s • Currently running 20 innovation programs, in every industry sectors • Total amount of annual funding (grant, loans) app. 550 million euros - funding up to 100 % of the costs • Focus on high tech companies and internationalization of the firms 14

Special themes in the Finnish system Cooperation • Many publicly funded programmes require cooperation between firms themselves, and between firms and research insititutes • Clear job descriptions. On the top of that cooperation is the most effective, it’s more a stage of mind ? • OSKE – Programme is a change - agent programme which initiates cooperation within an industry 15

Special themes in the Finnish system Involvement at the project development stage • Business parks are not involved in the development stage of the university research programs (however help to screen possibilities) • Some university projects are funded by Tekes (Finnish Funding Agency for Technology and Innovation), requires a plan how to commercialize the innovation • Legistlation regarding universities is changing, focus also on the business - and other impact on the society • Business parks should have a role, a bridge between research and the commercialization • The Centre Of Expertise Programms are part of a coordinated policy and thus 16

Special themes in the Finnish system Funding • Still having a problem in the seed stage financing, especially in biotech - Business - angels • Business parks usually don’t provide funding, but help in applying for it • A start –up entrepreneur can apply for Tekes-funded TULI investment that is normally intented for the preparation of market surveys by external consultants • Funding at the later stage is easier to find • Venture capital market is already well - developed 17