HCV THERAPY SELECTOR THE APP THAT ALLOWS EVERY

HCV THERAPY SELECTOR THE APP THAT ALLOWS EVERY DOCTOR TO PRACTICE: • EVIDENCE BASED MEDICINE WITHIN 1 MINUTE • SHARED DECISION MAKING

Public health problems Hepatitis C Mortality of chronic hepatitis C High mortality About 500 Dutch patients a year die from liver diseases Guidelines anno 2017 Quality usually good Evidence based (AASLD) or expert-based (EASL) caused by a hepatitis infection. Effective treatments Therapy Selection? Lack of awareness Penetration The deaths are "largely avoidable", because effective treatments against hepatitis B and C are available. There is no other known infectious disease in the Netherlands of which so many people die year after year, except possibly influenza. Therapeutic options presented without success rates: how to choose the option that fits your patient? expert hepatology centers: general hospitals: general practitioners: patients: good poor

What is HCV Therapy Selector? Guideline recommendations Evidenced-based chance of cure: Treatment specific Information Everywhere within 1 minute available: for patient profiles based on genotype, previous treatment history and cirrhosis stage for 80 patient profiles of hepatitis C infection about side effects, cost and reimbursement Patient-profile tailored information to facilitate selection of the best fitting treatment

HCV Therapy Selector complements guidelines 1 Guideline recommendations are expert-based, variably evidenced-based. 2 Guideline recommendations do not give crucial information about the cure rate to be expected. 3 Searching patient-specific guideline information takes time 4 5 Guideline recommendation give many therapeutic options. It is usually unclear which is best fitting your patient with regard to cure rate, adverse-effects and costs. Guideline recommendations due to its size, physician jargon, and complexity do not facilitate shared decision making. Patient profile data are evidence-based 1 Patient-profile data inform about the chance of cure, and provides treatmentspecific information on cost 2 Searching patient-specific profile data takes less than 1 minute. Patient-profile data information give many therapeutic options. It is usually clear which is best fitting your patient with regard to cure rate, adverse -effects and costs. Patient-profile data information due to its simplicity and easy accessibility facilitates shared decision making 3 4 5

Trend 2017 Individualizing HCV Therapy ! How do I do that?

Added value of HCV Therapy Selector: Tool to individualize HCV Therapy Evidenced-based chance of cure: Context-based Rx selection of all published treatment regimens Patient preference: side effects, efficacy. Doctor preference: experience, pathophysiology. Information available within 1 minute : Smartphone app Patient profile selection: 5 clicks Treatment selection: 5 clicks