GREGOR MENDEL Gregor Mendel was an Austrian monk
- Slides: 40
GREGOR MENDEL Gregor Mendel was an Austrian monk who studied genetics and observed how these traits were inherited over several generations.
GREGOR MENDEL His work was REALLY important to understanding inheritance. He studied what happened when he bred different kinds of pea plants (ex. green vs. yellow, short vs. tall, round vs. wrinkly) From his experiments he came up with several conclusions.
WHAT DID HE LEARN FROM HIS STUDIES? Biological inheritance is determined by “factors” (genes within our DNA )that are passed on from one generation to the next. Different forms of these genes determine our physical traits. For every gene, we inherit two alleles (one allele from each parent).
WHAT DID HE LEARN FROM HIS STUDIES? trait: specific characteristic that varies from one individual to another allele: one of a number of different forms of a gene locus: the location of a gene on a chromosome
MENDEL’S THREE PRINCIPLES Principle (Law) of Segregation § states that the two different alleles for a gene segregate independenty from one another during meiosis
MENDEL’S THREE PRINCIPLES Principle (Law) of Independent Assortment § states that different traits sort and are inherited independently of one another when sex cells are formed
MENDEL’S PRINCIPLES (A SUMMARY) For every gene, we inherit two copies (one allele from each parent) Blonde Hair Brown Eyes Blonde Hair Blue Eyes Brown Hair Brown Eyes
IF WE HAVE TWO SETS OF MANUALS, HOW DO WE KNOW WHICH DIRECTIONS TO FOLLOW? If we have two alleles for every trait, how does our body pick which one to express? Blonde Hair Brown Eyes Blonde Hair Blue Eyes Brown Hair Brown Eyes
IF WE HAVE TWO SETS OF MANUALS, HOW DO WE KNOW WHICH DIRECTIONS TO FOLLOW? When we get directions from each parent, it is a combination of the different directions that determine our traits.
MENDEL’S THREE PRINCIPLES Principle (Law) of Dominance § states that when two or more forms of a gene (alleles) exist for a single trait, some alleles are dominant while others are recessive
PRINCIPLE OF DOMINANCE Some alleles are dominant and others are recessive. Organisms with a dominant allele for a particular trait WILL exhibit that trait, because the dominant allele overpowers the recessive allele.
PRINCIPLE OF DOMINANCE A recessive trait will only show in in the organism when BOTH alleles are recessive – that is, when the dominant allele is NOT present.
PUNNETT SQUARES A Punnett square is a useful tool used to determine or predict the probability that offspring will have certain traits after a genetic cross.
PUNNETT SQUARES: PROBABILITY § Probability: the likelihood that a particular event will occur § Because each organism has two alleles for each gene there is an equal (50/50) chance of giving either allele to an offspring
PUNNETT SQUARES: TERMS Genotype: genetic makeup of an organism (alleles) § Genotype sounds like genes Phenotype: physical characteristics/appearance of an organism § Phenotype sounds like physical
PUNNETT SQUARES: TERMS Homozygous: an organism with two identical alleles for a particular trait Heterozygous: an organism with two different alleles for the same trait
LET’S USE THOSE WORDS IN AN EXAMPLE Homozygous for the tall trait – “TT” is the genotype, “tall” is the phenotype Heterozygous for the tall trait – “Tt” is the genotype, “tall” is the phenotype Homozygous for the short trait – “tt” is the genotype, “short” is the phenotype
PUNNETT SQUARES: RULES Use letters to stand for alleles Dominant alleles are noted with a CAPITAL ( D ) letter Recessive alleles for the same trait are noted with the lowercase ( d ) of the same letter.
PUNNETT SQUARES: RULES Parental genotypes are shown along the top and side of the Punnett square. § Write one parent’s alleles on the top, and write the other on the side § Put one letter next to each cell, and drag alleles across or down so that there are two alleles in each square.
PUNNETT SQUARES: RULES Each of the four squares represents a possible genotype of the offspring § These are just probabilities!
PUNNETT SQUARE PRACTICE 1. A homozygous tall (TT) pea plant is crossed with a homozygous short (tt) pea plant:
PUNNETT SQUARE PRACTICE A homozygous red (RR) flower is crossed with a heterozygous red (Rr) flower:
PUNNETT SQUARE PRACTICE A heterozygous funny (Ff) bird is crossed with a heterozygous funny (Ff) bird:
OFFSPRING RATIOS When you have two homozygous parents? § Genotype Ratio: ____ Phenotype Ratio: ____ When you have one homozygous and one heterozygous parent? § Genotype Ratio: ____ Phenotype Ratio: ____ When you have two heterozygous parents? § Genotype Ratio: ____ Phenotype Ratio: ____
MULTIPLE GENERATIONS Sometimes, we need to do a Punnett square to follow more than one generation. P F 1 F 2 Generations: parents first filial generation second filial generation
TEST CROSSES If you need to figure out the genotype of a parent with the dominant trait, you can do a test cross. This is done by crossing that parent with a homozygous recessive organism.
TEST CROSSES If any offspring show the recessive allele, you know that the dominant parent is heterozygous.
TEST CROSSES If none of the offspring show the recessive allele, you know that the dominant parent is homozygous.
EXAMPLE: A man with free earlobes wants to know if he is homozygous or heterozygous for that trait. He marries a woman with attached earlobes (the recessive trait). His first child has attached earlobes. The man has thus found out that he is _____________.
GOING BEYOND DOMINANT AND RECESSIVE ALLELES Some alleles are neither dominant nor recessive – many traits are controlled by more than one allele or by multiple genes…
INCOMPLETE DOMINANCE Incomplete dominance: a situation in which one allele is not completely dominant over another Because neither trait dominates the other, sometimes the alleles are written differently (ex. RW, C r C w , DD’) Examples are: flowers (red/pink/white), hair (curly/wavy/straight), fur (long/short)
IDENTIFYING INCOMPLETE DOMINANCE Notice that the offspring show a third phenotype that is different from the parents The offspring phenotype is a MIX or BLEND of the parental traits
IDENTIFYING INCOMPLETE DOMINANCE What happens when we cross a red (RR) flower with a white (WW) flower? The offspring look pink
CODOMINANCE codominance: a situation in which both alleles of a gene contribute to the phenotype of the organism § What does the prefix “co-“ mean? to share Because neither trait dominates the other, sometimes the alleles are written differently (ex. RW, C r C w , DD’) Examples are: cows (red/roan/white), flowers (red/spotted/white), blood type (A/AB/B)
IDENTIFYING CODOMINANCE Notice that the offspring show a third phenotype that is different from the parents The offspring phenotype has both parental traits appearing TOGETHER
IDENTIFYING CODOMINANCE What happens when we cross a pure red (RR) cow with a pure white (WW) cow? The offspring look roan spotted with red & white
IDENTIFYING CODOMINANCE What happens when we cross a pure red (RR) cow with a pure white (WW) cow? The offspring look roan spotted with red & white
POLYGENIC TRAITS Traits controlled by two or more genes are said to be polygenic. Polygenic traits show a wide range of phenotypes because different combinations of alleles on these genes produce many different traits.
POLYGENIC TRAITS For example, hair color and eye color are controlled by more than one gene and therefore have more than two phenotypes.
POLYGENIC TRAITS And, the wide range of skin color in humans is due to more than four different genes that control this trait.
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