GRAVES DISEASE Katie Panter CIS 1020 Final Project
- Slides: 8
GRAVES’ DISEASE Katie Panter CIS 1020 Final Project
WHAT IS GRAVES’ DISEASE? Ø A disease of the immune system Ø The body produces antibodies that mimic thyroid stimulating hormone Ø Leads to an overproduction of thyroid hormone Ø Result is an increase in metabolic rate Katie Panter CIS 1020 Final Project
Symptoms Bulging eyes Increased heart rate Weight loss Goiter Heat intolerance Pre-tibial myxedema (swelling of the shins) Katie Panter CIS 1020 Final Project
DIAGNOSIS RISK FACTORS IMMUNE CELLS INVOLVED Ultrasensitive TSH Test Individuals With Type 1 Diabetes Thyroid Cells Produce Cytokines Thyroid Scan Low Levels of Vitamin D Significant Increase in BCell Production Radioactive Iodine Uptake Test More Common in Females than Males Functional Defect in Natural Killer Cells TSH Antibody Test Individuals with Rheumatoid Arthritis CD 8 Cells are Suppressed Katie Panter CIS 1020 Final Project
Katie Panter CIS 1020 Final Project
TREATMENT �Surgical Removal of the Thyroid Gland �Anti-thyroid Drugs �Radioiodine Treatment Katie Panter CIS 1020 Final Project
Recurrence Of Graves’ Disease After Treatment Percentage of Patients with Recurrent Graves Disease Following Treatment 6, 90% 3, 10% Patients with Partial Thyroidectomy Patients with Radioiodine Therapy Patients with Total Thyroidectomy Patients with Anti-Thyroid Drugs 89, 70% Katie Panter CIS 1020 Final Project
Katie Panter CIS 1020 Final Project Marti Feldman
