Graded potential vs action potential graded potentials current
- Slides: 33
Graded potential vs action potential • graded potentials – current flow, amplitude - post-synaptic potentials • Action potentials – – – Trigger zone threshold voltage All-or-none Channel activity Refractory period Coding for stimulus intensity
Graded potential – amplitude decreases away from point of channel opening
Graded potential • Amplitude is directly proportional to the strength of the stimulating event • Depolarization wave known as local current flow • Strength depends on how much charge enters the cell • Decreases in strength as it travels through the cytoplasm • Can be depolarizing or hyperpolarizing
Graded potential – amplitude decreases away from point of channel opening
Action potential -Initiated if a threshold depolarization is reached at the trigger zone -Also called a spike -Always the same amplitude -Amplitude does not diminish -“All or none”, essential for long distance propogation
overshoot After hyperpolarization (undershoot)
Movement of ions through channels during the action potential (ion conductance)
The voltage gated Na+ channels • Has two gates: an activation gate and an inactivation gate (gate can be opened, gate can be locked)
Refractory period • Another action potential cannot fire when the inactivation gate is latched. • Action potentials cannot overlap • The absolute refractory period • Limits the rate of spike frequency • Important for frequency coding
Resting membrane potential is not restored, Na+ channel gates are unlatched (inactivation Is removed)
Coding for stimulus intensity
Coding for stimulus intensity
NO lecture on Friday • • Today How are action potentials propagated? Factors that affect conduction speed The consequences of abnormal levels of extracellular K+
Coding for stimulus intensity
Coding for stimulus intensity
How does an action potential spread?
What causes adjacent voltage gated sodium channels to open?
Low resistance to current flow in large diameter axons. (wide water pipe)
Mammalian axons are very thin, and action potential are conducted quickly.
Mammalian axons are insulated by myelin sheaths (myelinated axons).
What will abnormally high levels of extracellular K+ cause?
Abnormally high levels of K+ will cause • Resting membrane potential will be shifted toward action potential threshold • Get too much excitation (too many action potentials)
Abnormally low K+ • Membrane resting potential hyperpolarizes • Cell is far away from threshold for action potential
- Neuronal pool
- Types of graded potentials
- Graded potentials
- Graded vs action potential
- Difference between action and graded potential
- Sources of bioelectric potentials
- Hypopolarization
- Neuromuscular junction ach
- Action potential resting potential
- Action potential resting potential
- Ipsp vs epsp
- Postsynaptic potentials
- Table of standard reduction potentials
- Multiple expansion
- Cathode anode standard reduction potential
- Electroch
- Use the tabulated half-cell potentials to calculate
- Summation of postsynaptic potentials
- U=ts-pv
- Maxwell thermodynamic relations
- Thermodynamic potentials
- Free energy
- Electromagnetic potentials
- Magnitude electric field
- Line current and phase current
- Power formula three phase
- Drift current and diffusion current in semiconductor
- Ac systems lesson 4
- Drift vs diffusion current
- Drift current and diffusion current in semiconductor
- The constant current region of a fet lies between
- Delta to wye conversion balanced
- Holding current and latching current
- Drift current density unit