GMO regulation in New Zealand Dr Manda Safavi

GMO regulation in New Zealand Dr Manda Safavi Advisor New Organisms, EPA, New Zealand

At the EPA, we protect the environment for a better way of life: o o o Exclusive Economic Zone (EEZ) Nationally Significant Proposal (NSP) Applications Emissions Trading Scheme (ETS) Operations Hazardous Substances New Organisms

New organism? A new organism is a) An organisms belonging to a species that was not present in New Zealand immediately before 29 July 1998 b) Genetically Modified Organisms (GMOs) GMOs a) Have been modified by in vitro techniques, or b) Are inherited or otherwise derived, through any number of replications, from any genes or other genetic material which has been modified by in vitro techniques

Who needs approval from us • • Import a new organisms (incl. GMO) Develop a new organisms (incl. GMO) Filed trail a new organisms (incl. GMO) Release a new organisms (incl. GMO)

Import GMOs into containment Figure taken from www. sample 6. com

What is Sample 6? Figure taken from www. sample 6. com

s n es raditio u l a t d yv lth hea munit lture an c i l Pub ety/comheir cu i t ü Soc ri and t n ü Mao ronme i v ü n y E nom ü Eco ü 30 30 w w d d Import a GMO

Develop (In relation to organisms other than incidentally imported new organisms) means: Ø Genetic modification of an organism Ø Regeneration of a new organism from biological material of the organism that cannot, without human intervention, be used to produce the organism Ø Fermentation of a micro-organism that is a new organism

Develop a GMO rapid 30 30 w w d d Full-assessment 10 q q Non low-risk 2 * 30 working days HSNO Committee Outcome-based controls q q Low-risk 10 working days CE Prescriptive controls w d

GMO field test GM pine trees: To field test in containment pine trees with genetic modifications to alter plant growth/biomass acquisition, reproductive development, herbicide tolerance, utilisable biomass, wood density and dimensional stability GM cattle: To field test genetically modified cattle with extra bovine genes, the insertion of the human myelin basic protein gene, and the deletion of the bovine βlactoglobulin gene. Genes will be expressed in the milk of the cattle.

Facilitate s Iwi c ga onsultatio n Pub lic h eari ng NK T Te T Her en GMO field trial Comp re repor hensive t s s ition e d u l a tr va h ealt munity re and h c u i l lt Pub ety/comheir cu i t c ü So ri and t n ü Mao ronme i v ü En omy n ü Eco Statutory ob ligation ü

GM release Conditional release: Pexa-Vec: a live-attenuated vaccina virus containing three genetic modifications to be used in phase 3 clinical trial for hepatocellular carcinoma patients Wild type virus GM vaccina virus (Pexa-Vec) Thymidine kinase Human h. GM-CSF Recruits T-cells to cancer cells Full release: none Lac. Z

Māori engagement o Kaupapa Kura Taiao (KKT): EPA’s Māori policy and operations group o Ngā Kaihautū Tikanga Taiao (NKTT): Māori advisory group of the EPA o Te Herenga network: EPA’s national network of Māori environmental practicioners and resource managers

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