GLYCERITES N SANTHI PRIYA Mpharm Asst Professor Chalapathi

  • Slides: 6
Download presentation
GLYCERITES N. SANTHI PRIYA Mpharm. , Asst. Professor Chalapathi institute of pharmaceutical sciences DEPARTMENT

GLYCERITES N. SANTHI PRIYA Mpharm. , Asst. Professor Chalapathi institute of pharmaceutical sciences DEPARTMENT OF PHARMACEUTICS

GLYCERITES • Glycerites are viscous solutions of medicaments in not less than 50% by

GLYCERITES • Glycerites are viscous solutions of medicaments in not less than 50% by weight of glycerin intended to be applied externally • These viscous, demulcent and soothing preparations are widely used to treat throat disorders • Glycerites are also used as mouth wash, gargles, mouth paints, dental and gum treatments, applied topically or used as ear drops

BORAX GLYCERIN Borax glycerin I. P • Borax -12 g • Glycerin -88 gm

BORAX GLYCERIN Borax glycerin I. P • Borax -12 g • Glycerin -88 gm Principle : • Borax is soluble in 16 parts of water and in 1 part of boiling water and 1 part of glycerin • In dry state it is efflorescent • Its aqueous solution is alkaline and precipitates metals as insoluble borates • But with glycerin it produces glyceroboric acid • Borax is toxic if taken internally • Glycerin is soothing agent and due to its viscosity it keeps the drug in contact with affected are for prolonged periods of time

COMPOUNDING : 1. 2. 3. Triturate the powdered borax with glycerin to produce smooth

COMPOUNDING : 1. 2. 3. Triturate the powdered borax with glycerin to produce smooth dispersion Warm the mixture using water bath with constant stirring to get solution Filter if necessary Container and storage : store in fluted bottle • Provide brush, store in well closed container in dry place Category and direction to use: BACTERIOSTATIC Label: For external use only. To be used sparingly Patient counselling: Do Not Swallow

STARCH GLYCERIN Starch-10 gm Benzoic acid-0. 2 g Purified water -20 ml Glycerin to

STARCH GLYCERIN Starch-10 gm Benzoic acid-0. 2 g Purified water -20 ml Glycerin to make -100 gm Starch has absorbent and demulcent properties • When jelled with glycerin it provides a non-fatty emollient base • Starch is insoluble in water and glycerin • When heated it produces translucent jelly • Benzoic acid is preservative

Compounding • Triturate the starch and benzoic acid with water in porcelain dish to

Compounding • Triturate the starch and benzoic acid with water in porcelain dish to produce smooth dispersion • Add glycerin and heat the mixture using sand bath with constant stirring to get transparent jelly • Strain through muslin cloth • Category : Emollient, Pill excipient • Label: For external use only