Glucocorticoids induce differentiation of monocytes towards macrophages that

Glucocorticoid receptor activation directs CD 14+ monocytes towards a tissue resident macrophage phenotype. Esther

Proteome analysis of CD 14+ monocytes cultured in the presence or absence of dexamethasone

GC-macrophages form erythroblast clusters with increased frequency and erythroblast composition. Esther Heideveld et al.

GC-macrophages can bind erythroid cells and phagocytose pyrenocytes. Esther Heideveld et al. Haematologica 2018;

CD 163+ macrophage populations in human BM and FL. (A) Representative dot plots of

Slides: 6

Download presentation

Glucocorticoids induce differentiation of monocytes towards macrophages that share functional and phenotypical aspects with erythroblastic island macrophages by Esther Heideveld, Lea A. Hampton-O’Neil, Stephen J. Cross, Floris P. J. van Alphen, Maartje van den Biggelaar, Ashley M. Toye, and Emile van den Akker haematol Volume 103(3): 395 -405 February 28, 2018 © 2018 by Ferrata Storti Foundation

Glucocorticoid receptor activation directs CD 14+ monocytes towards a tissue resident macrophage phenotype. Esther Heideveld et al. Haematologica 2018; 103: 395 -405 © 2018 by Ferrata Storti Foundation

Proteome analysis of CD 14+ monocytes cultured in the presence or absence of dexamethasone revealed two distinct macrophage populations. Esther Heideveld et al. Haematologica 2018; 103: 395 -405 © 2018 by Ferrata Storti Foundation

CD 163+ macrophage populations in human BM and FL. (A) Representative dot plots of erythroid cells characterized by the expression of CD 71 high and CD 235 a in total human BM (n=4) and FL mononuclear cells (n=4). Esther Heideveld et al. Haematologica 2018; 103: 395 -405 © 2018 by Ferrata Storti Foundation