Genome analysis of myelodysplastic syndromes among atomic bomb

Genome analysis of myelodysplastic syndromes among atomic bomb survivors in Nagasaki by Masataka Taguchi, Hiroyuki Mishima, Yusuke Shiozawa, Chisa Hayashida, Akira Kinoshita, Yasuhito Nannya, Hideki Makishima, Makiko Horai, Masatoshi Matsuo, Shinya Sato, Hidehiro Itonaga, Takeharu Kato, Hiroaki Taniguchi, Daisuke Imanishi, Yoshitaka Imaizumi, Tomoko Hata, Motoi Takenaka, Yukiyoshi Moriuchi, Yuichi Shiraishi, Satoru Miyano, Seishi Ogawa, Koh-ichiro Yoshiura, and Yasushi Miyazaki haematol Volume 105(2): 358 -365 February 1, 2020 © 2020 by Ferrata Storti Foundation

Patients’ characteristics. Masataka Taguchi et al. Haematologica 2020; 105: 358 -365 © 2020 by

Somatic mutations identified in coding exons of five patients in the proximally exposed group.

Pattern of nucleotide substitutions in the whole genomes of three patients in the proximally exposed group. Masataka Taguchi et al. Haematologica 2020; 105: 358 -365 © 2020 by Ferrata Storti Foundation

Somatic mutations in myelodysplastic syndromes (MDS) among A-bomb survivors. Masataka Taguchi et al. Haematologica

Frequencies of somatic gene mutations in the proximally and distally exposed groups. Masataka Taguchi

Frequencies of mutated genes categorized by assumed functional pathway. Masataka Taguchi et al. Haematologica

Copy number alterations in myelodysplastic syndromes (MDS) among A-bomb survivors. Masataka Taguchi et al.

Copy number alterations and mutations of candidate genes in the frequently affected region on chromosome 11 q. Masataka Taguchi et al. Haematologica 2020; 105: 358 -365 © 2020 by Ferrata Storti Foundation